Reviewers criticized the study's methods and suggested focusing on drug mechanisms instead of repositioning due to social media data quality concerns.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
Machine learning helps find new uses for existing drugs, improving healthcare.
6 citations
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January 2022 in “Database” The data set helps improve predictions of how substances are absorbed through pig skin.
Optimized liposomes can improve drug delivery and effectiveness.
September 2024 in “International Journal of Applied Pharmaceutics” A reliable method was developed to measure Finasteride and Tadalafil in rat blood.
66 citations
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June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
April 2026 in “Therapeutic Advances in Drug Safety” Finasteride is high-risk for cognitive disorders, while Carbidopa/Levodopa, Topiramate, and Clonazepam are moderate-risk.
1 citations
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June 2017 in “International Journal of Toxicology” Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.
January 2002 in “Europe PMC (PubMed Central)” The model successfully simulates human hair growth and patterns, including hair loss types.
5 citations
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July 2019 in “Applied statistics/Journal of the Royal Statistical Society. Series C, Applied statistics” Case-only trees and random forests improve predictions of treatment effects in clinical trials.
147 citations
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September 2001 in “Computer graphics forum” The authors created a realistic and efficient method to simulate hair movement by combining fluid dynamics with individual hair strand behavior.
11 citations
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June 2017 in “Mathematical Medicine and Biology A Journal of the IMA” The model helps understand and improve treatments for alopecia areata by simulating hair growth and immune cell interactions.
September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
20 citations
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January 2009 in “Chemical Papers” Both HPSAM and PLS methods accurately measure minoxidil and tretinoin concentrations.
34 citations
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January 2020 in “IEEE Access” A model called PM-DBiGRU was developed for analyzing sentiments in drug reviews, and it performed better than other models, but struggled with complex sentences and situations requiring background knowledge.
August 2022 in “Sovremennye tehnologii v medicine” Barophoresis is a feasible and safe method for treating chronic generalized periodontitis.
14 citations
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January 2012 in “Proteins” Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
March 2024 in “Research Square” The model helps understand alopecia areata and suggests ways to improve treatment by targeting immune issues.
Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.
April 2018 in “Journal of Ayurvedic and herbal medicine” Computational methods can speed up and improve the development and safety of herbal drugs.
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
38 citations
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January 2001 in “Neuroepidemiology” The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.
A few users dominate Reddit discussions on JAK inhibitors, highlighting social media's potential for tracking drug safety but needing expert oversight.
January 2026 in “Microsystems & Nanoengineering” New technologies replicate human skin for testing without animals.
70 citations
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August 2019 in “European Journal of Medicinal Chemistry”
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
8 citations
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March 2021 in “Drug testing and analysis” Researchers improved a method to more accurately estimate when and how long a drug was taken using hair analysis.
5 citations
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April 2024 in “Science China Materials”