research Hydrogel-Forming Microneedles for Transdermal Drug Delivery
Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
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120-150 / 1000+ resultsresearch Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation
Cathelicidins could treat skin issues but face challenges like safety and resistance.
research Exploring the Efficacy and Potential Mechanisms of Topical Periplaneta americana (L.) Extract in Treating Androgenetic Alopecia in a Mouse Model: A Systems Pharmacology and Skin Microbiome Analysis
Periplaneta americana extract promotes hair growth and is safe for treating hair loss.
research Application of microneedle patches for drug delivery; doorstep to novel therapies
Microneedle patches could replace injections but need more development for better use in medicine.
research Exosomes in stroke management: A promising paradigm shift in stroke therapy
Exosome therapy could revolutionize stroke treatment, but more research is needed for human use.
research Lysophospholipid Mediators in Health and Disease
Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
research Cepharanthine Dry Powder Inhaler for the Treatment of Acute Lung Injury
Cepharanthine dry powder inhalers may effectively treat acute lung injury by reducing inflammation.
research Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis
Skin acetyl-CoA synthesis is crucial for overall lipid balance.
research Particulate 3D Hydrogels of Silk Fibroin-Pluronic to Deliver Curcumin for Infection-Free Wound Healing
The hydrogel effectively heals wounds and fights bacteria.
research Microneedle-Mediated Transdermal Drug Delivery for the Treatment of Multiple Skin Diseases
Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
research Therapeutic Effects of Alkaloids on Influenza: A Systematic Review and Meta-Analysis of Preclinical Studies
Alkaloids help fight influenza in animals but need more research for human use.
research Extracellular vesicles as human therapeutics: A scoping review of the literature
Extracellular vesicles show promise as treatments but need more research for safety and effectiveness.
research Topical Delivery of Atraric Acid Derived from Stereocaulon japonicum with Enhanced Skin Permeation and Hair Regrowth Activity for Androgenic Alopecia
AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.
research Microneedles as transdermal drug delivery system for enhancing skin disease treatment
Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
research Cell death in skin function, inflammation, and disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research A regulatory perspective on pharmacokinetic/pharmacodynamic modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Single and repeated dose of finasteride topical solution in subjects with androgenetic alopecia: A pharmacokinetic and pharmacodynamic study
Finasteride solution helps treat hair loss.
research Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic (TMDD-PD) Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-linear Pharmacokinetics
Finasteride and dutasteride's effects are mainly due to target binding saturation and slow enzyme turnover.
research 3P's (Pharmacokinetic, Pharmacodynamic, and Pharmacogenomic) of Valproate: What's New?
New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Pharmacodynamics and pharmacokinetics of P-3074, a new finasteride topical solution, administered at four different doses
P-3074 effectively blocks scalp DHT better than oral finasteride.
research Bipolar Disorders and Valproate: Pharmacokinetics,Pharmacodynamics, Therapeutic Effects and Indications of Valproate: Review of Articles
Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.
research A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetic, Pharmacodynamic, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia
IVL3001 is safe, effective, and better than oral finasteride for treating hair loss.
research Saturable Binding of Finasteride to Steroid 5α-reductase as Determinant of Nonlinear Pharmacokinetics
Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
research Modeling the pharmacodynamics of nandrolone doping drug and implications for anti‐doping testing
The document concludes that finasteride can reduce nandrolone detection in doping tests, suggesting frequent testing and setting metabolite level thresholds for detection.
research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.
research Plucked Human Hair Shafts and Biomolecular Medical Research
Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
research 41949 Raman spectroscopy of alopecia drugs to assess their potential for laser-assisted drug delivery
Raman spectroscopy is promising for measuring and enhancing drug delivery in alopecia treatments.
research Niosomes as Vesicular Nanocarriers in Cosmetics: Characterisation, Development and Efficacy
Niosomes improve delivery and effectiveness of cosmetic ingredients.
research A finasteride patch for the treatment of androgenetic alopecia: A study of promoting permeability strategy using synthetic novel O-acylmenthols combined with ion-pair
The finasteride patch effectively treats hair loss by enhancing skin absorption.