research Construction strategies of skin organoids: A review
A unified framework is needed to improve skin organoid construction for research and clinical use.
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30 / 1000+ results research Generation of Human Induced Pluripotent Stem Cell-derived Planar Hair-bearing Skin Organoids Using an Air-Liquid Interface Culture System
The method creates skin organoids with hair follicles for research on skin conditions and treatments.
research Innovations in skin microphysiological systems for nonclinical testing and FDA modernization
New technologies replicate human skin for testing without animals.
research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology
3D human skin models show promise for dermatology but face challenges in standardization and cost.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
research Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids
A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Establishment and characterization of a canine keratinocyte organoid culture system
A new method to study dog skin diseases using lab-grown skin cells was developed.
research Hair follicle organoids: advances in construction, applications, and translational challenges
Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
research Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle‐Shaped Microfluidic Device
Scientists developed a new way to create skin-like structures from stem cells using a special 3D gel and a device that improves cell organization and increases hair growth.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Functional Skin Grafts: Where Biomaterials Meet Stem Cells
Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
research Novel Technologies for Exploring the Skin–Brain Axis
Advanced technologies can improve understanding and monitoring of skin-brain interactions.
research Progress and perspectives on hydrogel-assisted skin organoids
Hydrogel-based methods improve skin organoid development for medical and research applications.
research Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling
Hair follicle systems are being engineered to better mimic natural hair follicles for studying hair disorders and testing treatments.
research 3D bioprinting of hepatocyte-derived exosome-reinforced skin organoid for efficient skin regeneration
3D bioprinted skin using liver cell exosomes helps heal wounds better.
research Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection
Skin organoids can model tuberculosis infection and help test treatments.
research Advancements in hydrogel-based design and applications of hair follicle organoids
Hydrogel-based hair follicle organoids could help treat hair loss and improve drug testing.
research Understanding skin morphogenesis across developmental, regenerative and evolutionary levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Tracking adult stem cells
A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Development of pluripotent stem cell-derived epidermal organoids that generate effective extracellular vesicles in skin regeneration
Stem cell-derived organoids can improve skin healing.
research Integrating stem cell biology and organoid technology for skin regenerative therapies
Combining stem cells and organoids could improve skin regeneration treatments.
research Cultured Human Foreskin as a Model System for Evaluating Ionizing Radiation-Induced Skin Injury
Human foreskin does not show aging or reduced cell growth after radiation, and H2A.J is not a good marker for radiation-induced aging.
research The empowering influence of air-liquid interface culture on skin organoid hair follicle development
Air-liquid interface culture improves hair follicle development in skin organoids.
research Organoids in skin wound healing
Skin organoids help improve wound healing and tissue repair.
research Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell–Derived Skin Organoids to Inflammation and Injury
Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Microtechnology-based methods for organoid models
Microtechnology methods improve organoid production for medical research.