18 citations
,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
15 citations
,
June 2024 in “Frontiers in Pharmacology” Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
9 citations
,
August 2023 in “Journal of Investigative Dermatology” IL-15 helps hair grow longer and stronger by extending the growth phase and reducing cell death.
9 citations
,
August 2021 in “Biomedicines” 17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
8 citations
,
September 2022 in “Human genomics” Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.
7 citations
,
June 2025 in “International Journal of Molecular Sciences” Vitexin shows promise as a cancer treatment by affecting key cellular processes and pathways.
7 citations
,
January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
6 citations
,
June 2024 in “Medical Review” Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.
3 citations
,
January 2025 in “Burns & Trauma” Glucose metabolism is crucial for wound healing but can delay healing in chronic wounds due to increased stress and inflammation.
3 citations
,
December 2024 in “International Journal of Dermatology” Premature hair graying is caused by genetics, stress, and lifestyle, and affects mental health.
3 citations
,
January 2023 in “JEADV Clinical Practice” IL-17 is more important than IFN-γ in causing severe hair loss in chronic alopecia areata.
2 citations
,
June 2025 in “Preprints.org” Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
2 citations
,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
2 citations
,
July 2023 in “Animals” FGF10 and non-coding RNAs are important for cashmere goat hair follicle development.
1 citations
,
November 2024 in “EMBO Reports” Deleting Gpr54 speeds up hair growth and regeneration.
1 citations
,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
1 citations
,
May 2022 in “IntechOpen eBooks” Natural products might help treat COVID-19, but current drugs like hydroxychloroquine haven't worked.
May 2026 in “Discover Oncology” Targeting LGR4 may help treat cancer by reducing cancer stem cell traits and drug resistance.
January 2026 in “Therapeutics” SCUBE3 is a potential target for cancer and alopecia treatment but is challenging to target due to its varied roles.
January 2026 in “Pharmaceutics” New drug delivery systems show promise in effectively treating pathological scars.
December 2025 in “Cosmetics” New treatments for alopecia show promise in restoring hair growth by targeting immune and hormonal factors.
September 2025 in “Current Oncology” LncRNAs may help improve brain cancer treatment and diagnosis.
September 2025 in “Science Advances” PADI4 enzyme slows down cell growth in developing hair follicles.
June 2025 in “International Journal of Molecular Sciences” LncRNAs play a crucial role in muscle regulation and could help develop treatments for Duchenne muscular dystrophy.
April 2025 in “Frontiers in Pharmacology” Canagliflozin helps overcome progestin resistance in certain endometrial cancer cells.
September 2024 in “Journal of Cosmetic Dermatology” Ectoin helps prevent cortisone-induced skin problems and supports skin health.
November 2023 in “Plants” Compounds from Jatropha cordata bark have significant anti-inflammatory effects and could help with hair loss.
May 2023 in “Journal of Investigative Dermatology” Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
27 citations
,
April 2008 in “Journal of Biological Chemistry” HMG-CoA reductase is crucial for skin wound healing by regulating keratinocyte growth and blood vessel formation.
12 citations
,
May 2024 in “International Journal of Nanomedicine” Stem cell-derived vesicles show promise for healing diabetic wounds.