Search

for
Search:

Did you mean Placebo-Controlled?

GlossaryPlacebo-Controlled

comparison involves an inactive substance to test treatment efficacy

A placebo-controlled study is a type of clinical trial where one group of participants receives the experimental treatment, while another group receives a placebo—a substance with no therapeutic effect, often a sugar pill. This design helps researchers determine the actual effectiveness of the treatment by comparing outcomes between the treated group and the placebo group, thereby accounting for the placebo effect, where participants may experience perceived or actual improvements in their condition simply because they believe they are receiving treatment.

Related Terms

Sort by

Research

30 / 1000+ results

Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program

research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program

January 2024 in “American journal of clinical dermatology”

Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.

Comparison Between Dutasteride and Finasteride in Hair Regrowth and Reversal of Miniaturization in Male and Female Androgenetic Alopecia: A Systematic Review

research Comparison between dutasteride and finasteride in hair regrowth and reversal of miniaturization in male and female androgenetic alopecia: a systematic review

April 2024 in “Dermatology reports”

Dutasteride is more effective than finasteride for hair regrowth in male and female pattern hair loss, with similar side effects.

research Supplementary Material for: Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study

January 2019

RCS-01 cell therapy is safe and improves skin gene expression.

research Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study

6 citations , September 2019 in “Skin pharmacology and physiology”

RCS-01 therapy is safe and may improve skin structure by affecting gene expression.

research Treatment of alopecia areata with the janus kinase inhibitor upadacitinib: A retrospective cohort study

6 citations , February 2023 in “Journal of the American Academy of Dermatology”

Upadacitinib improved hair regrowth and quality of life in alopecia areata patients with minimal side effects.

research Methodologic considerations in evaluating early clinical outcomes of GT20029 for androgenetic alopecia

January 2026 in “Journal of Dermatological Treatment”

GT20029 showed some hair growth improvement, but longer studies are needed for better results.

Post-Finasteride Syndrome Update: Point/Counterpoint

research Post-Finasteride Syndrome (PFS) Update: Point/Counterpoint

January 2016 in “Hair transplant forum international”

Finasteride's link to health issues like male breast cancer, infertility, and prostate cancer needs more research through placebo-controlled trials to confirm.

research Medical therapy for frontal fibrosing alopecia: A review and clinical approach

37 citations , April 2019 in “Journal of The American Academy of Dermatology”

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

research [Photographic documentation of the effectiveness of 1 mg. oral finasteride in treatment of androgenic alopecia in the man in routine general practice in Switzerland].

4 citations , November 2001 in “PubMed”

1 mg/day oral finasteride significantly improves hair growth in men with male pattern baldness.

research Childhood alopecia areata: What treatment works best?

1 citations , January 2011 in “MOspace Institutional Repository (University of Missouri)”

Topical immunotherapy with SADBE and DPCP is most effective for short-term hair regrowth in children with severe alopecia areata.

Sesquiterpene-Enriched Extract of Curcuma Aeruginosa Roxb. Retards Axillary Hair Growth: A Randomized, Placebo-Controlled, Double-Blind Study

research Sesquiterpene-Enriched Extract of Curcuma aeruginosa Roxb. Retards Axillary Hair Growth: A Randomised, Placebo-Controlled, Double-Blind Study

5 citations , January 2018 in “Skin Pharmacology and Physiology”

Curcuma aeruginosa extract lotion significantly reduces underarm hair growth.

Safety and Clinical Efficacy of Kūlaris, an Herbal Supplement for Mild to Severe Acne Vulgaris: A 12-Week Randomized, Double-Blind, Placebo-Controlled Study

research Safety and Clinical Efficacy of KūlarisTM, an Herbal Supplement for Mild to Severe Acne Vulgaris – A 12-Week Randomized, Double Blind, Placebo-Controlled Study

September 2025 in “Clinical Cosmetic and Investigational Dermatology”

Kūlaris improved quality of life for acne sufferers without side effects.

A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata

research A randomized placebo-controlled single-center pilot study of the safety and efficacy of apremilast in subjects with moderate-to-severe alopecia areata

42 citations , November 2018 in “Archives of dermatological research”

Apremilast was not effective in treating moderate-to-severe alopecia areata.

$Finasteride for Treatment of Refractory Hemospermia: Prospective Placebo-Controlled Study$

research Finasteride for treatment of refractory hemospermia: prospective placebo-controlled study

13 citations , September 2011 in “International Urology and Nephrology”

Sublingual Minoxidil for the Treatment of Male and Female Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase 1B Clinical Trial

research Sublingual minoxidil for the treatment of male and female pattern hair loss: a randomized, double‐blind, placebo‐controlled, phase 1B clinical trial

5 citations , August 2021 in “Journal of The European Academy of Dermatology and Venereology”

Sublingual minoxidil safely promotes hair growth.

research Effects of finasteride in patients with inflammatory chronic pelvic pain syndrome: a double-blind, placebo-controlled, pilot study

65 citations , March 1999 in “Urology”

Finasteride didn't significantly improve ICPPS symptoms, more research needed.

Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women

research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women

3 citations , May 2018 in “Reproductive Sciences”

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

Safety And Efficacy Of Oral Administered Cepharanthine In Non-Hospitalized, Asymptomatic Or Mild COVID-19 Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

research Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial

3 citations , January 2025 in “Scientific Reports”

Cepharanthine is safe but not effective in significantly reducing COVID-19 recovery time.

A Randomized, Double-Blind, Placebo- and Active-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Alopecia Areata

research A randomized, double-blind, placebo- and active-controlled, half-head study to evaluate the effects of platelet-rich plasma on alopecia areata

205 citations , April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

Topical Sandalore, a Specific OR2AT4-Stimulating Odorant, Ameliorates Female Telogen Effluvium: Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

research 609 Topical Sandalore®, a specific OR2AT4-stimulating odorant, ameliorates female telogen effluvium: Randomized, double-blinded, placebo-controlled clinical trial

April 2019 in “Journal of Investigative Dermatology”

Sandalore®, a synthetic scent, improved hair loss and satisfaction in women with telogen effluvium.

Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study

research Growth factor concentrations in platelet‐rich plasma for androgenetic alopecia: An intra‐subject, randomized, blinded, placebo‐controlled, pilot study

13 citations , January 2020 in “Experimental Dermatology”

PRP growth factor concentrations vary, no significant hair growth difference found.

The Long-Term Effect of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo-Controlled Trial

research The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial

11 citations , May 2002 in “The Journal of Urology”

Finasteride doesn't harm bone density in older men with BPH.

Safety and Efficacy of Orally Administered Cepharanthine in Non-Hospitalized, Asymptomatic or Mild COVID-19 Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

research Safety and Efficacy of Oral administrated Cepharanthine in Non-hospitalized, asymptomatic or mild COVID-19 patients: A Double-blind, Randomized, Placebo-controlled Trial

1 citations , January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Cepharanthine is safe but not clearly effective in speeding up COVID-19 recovery.

Efficacy and Safety of a Drinkable Nutraceutical in Premenopausal Women with Telogen Effluvium: A 6-Month, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study

research Efficacy and Safety of a Drinkable Nutraceutical in Premenopausal Women with Telogen Effluvium: A 6-Month, Randomized, Multicenter, Double-Blind, Placebo-Controlled Study

November 2025 in “Dermatology and Therapy”

The drinkable supplement increased hair growth and was safe for women with hair loss.

Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial

research Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial

January 2025 in “MEDS Public Health and Preventive Medicine”

Spermidine supplements can help extend the hair growth phase and may be useful for treating hair loss.

Efficacy of Quadruple-Coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

research Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study

January 2024 in “Journal of neurogastroenterology and motility”

Quadruple-coated probiotics significantly improve IBS symptoms.

Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus® PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial

research Efficacy and Safety of a Proprietary Free Fatty Acid Rich Saw Palmetto Extract (USPlus® PRO) for Lower Urinary Tract Symptoms in Males: A Randomized, Double-Blind, Placebo-Controlled Trial

January 2026 in “Food and Nutrition Sciences”

USPlus PRO saw palmetto extract improves urinary symptoms and is safe for men.

research A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women.

10 citations , May 2007 in “PubMed”

1% topical minoxidil solution significantly improved hair growth in Japanese women with androgenetic alopecia, with no major side effects.

research Safety and efficacy of ALRV5XR in women with androgenetic alopecia or telogen effluvium: A randomised, double-blinded, placebo-controlled clinical trial

6 citations , June 2021 in “EClinicalMedicine”

ALRV5XR significantly improves hair density in women with hair loss and is well-tolerated.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations , September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.