126 citations
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August 2018 in “Molecular Systems Biology” Fibroblast state switching is crucial for skin healing and development.
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February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
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February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
11 citations
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April 2022 in “International Journal of Molecular Sciences” Understanding the Wnt/β-catenin pathway and photobiomodulation could improve diabetic wound healing.
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May 2017 in “Heliyon” Wound healing can help prevent hair loss from chemotherapy in young rats by increasing interleukin-1β signaling.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
10 citations
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May 2017 in “Wound Repair and Regeneration” Overexpression of ALK2 in hair follicles disrupts skin development and slows wound healing.
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December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Fibroblast behavior is key for skin structure and healing.
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July 2016 in “Journal of Dermatological Science” Regenerated hairs can regain their color if the wound occurs during a certain stage of hair growth, and this process is helped by specific skin cells and proteins.
April 2019 in “Journal of Investigative Dermatology” Calcium signals and SHH guide the direction of feather growth in chicken skin.
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January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
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July 2011 in “Wound Repair and Regeneration” New antiscarring strategies show promise, including drugs, stem cells, and improved surgical techniques.
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January 2025 in “Burns & Trauma” Machine learning and single-cell analysis improve understanding and treatment of wound healing.
5 citations
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December 2021 in “Journal of Investigative Dermatology” Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
August 2022 in “Biomedicines” Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.
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July 2015 in “British Journal of Dermatology” Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
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November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
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October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
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January 2006 in “BMC Cell Biology” Wnt signaling can improve skin healing by promoting epithelial growth.
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
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August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
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September 1991 in “Journal of Surgical Research” Understanding how fetal wounds heal could help improve healing in adults.
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December 2010 in “Dermatologic Surgery” Laser treatment can stimulate hair growth for male pattern hair loss.
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August 2018 in “Nature Communications” JunB is crucial for maintaining healthy skin and hair follicles.
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September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
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May 2022 in “Journal of Investigative Dermatology” Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
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February 2022 in “Scientific Reports” CD26+ fibroblasts improve skin healing and integration better than CD26− fibroblasts.
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August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
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September 2022 in “Journal of Investigative Dermatology” Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.
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April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.