January 2025 in “PLoS ONE” Aligned membranes improve wound healing by reducing scars and promoting skin regeneration.
2 citations
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May 2025 in “Frontiers in Immunology” Ursolic acid may help develop new anti-inflammatory drugs by affecting immune cells.
M-CSF-stimulated myeloid cells can turn into skin cells and help heal wounds and regrow hair.
October 2025 in “Journal of Nanobiotechnology” The hydrogel helps wounds heal better by reducing inflammation and promoting skin regeneration.
July 2025 in “International Journal of Molecular Sciences” Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
2 citations
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July 2022 in “The Kaohsiung Journal of Medical Sciences” FTY720 helps transplanted fat survive better by reducing immune rejection and improving blood vessel growth.
16 citations
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June 2025 in “Journal of Composites Science” Chitosan–hydroxyapatite biocomposites are promising for tissue engineering due to their safety and ability to support healing.
7 citations
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January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
13 citations
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April 2025 in “International Journal of Nanomedicine” The new gallic acid hydrogel speeds up wound healing and reduces scarring.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
1 citations
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August 2025 in “Biology Direct” Adipose tissue therapies have advanced from tissue to cell and cell-free treatments, showing promise but also limitations.
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
January 2026 in “Burns & Trauma” RNA modifications help heal wounds and could lead to new treatments.
263 citations
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February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
5 citations
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January 2025 in “Burns & Trauma” Machine learning and single-cell analysis improve understanding and treatment of wound healing.
130 citations
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September 2018 in “Cell Reports” Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
175 citations
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December 2014 in “PLoS Biology” Macrophages help activate hair follicle stem cells, affecting hair growth and skin repair.
24 citations
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May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
July 2024 in “Journal of Investigative Dermatology” Glutamine helps macrophages reduce inflammation and improve wound healing.
187 citations
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April 2019 in “npj Regenerative Medicine” Wharton's jelly secretomes are best for promoting blood vessel growth.
56 citations
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March 2015 in “Cell death and differentiation” Older skin has higher cancer risk due to inflammation and stem cell issues.
52 citations
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January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
13 citations
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February 2023 in “Pharmaceutics” Bioactive wound dressings can improve healing by promoting beneficial macrophage activity.
3 citations
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June 2025 in “Journal of Cellular and Molecular Medicine” CuATSM speeds up wound healing and reduces scarring.
27 citations
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May 2018 in “Journal of Dermatological Science” M2 macrophages, a type of immune cell, help in new hair growth on scars by producing growth factors.
26 citations
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April 2019 in “Advances in wound care” Tannic acid helps wounds heal faster in rats by activating certain cell signals and reducing inflammation.
16 citations
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January 2020 in “Diabetes” A new therapy sped up wound healing and reduced scarring in diabetic rats.
1 citations
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February 2023 in “International Journal of Molecular Sciences” Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.
1 citations
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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.