research Common Skin Diseases and Metabolic Syndrome: A Proinflammatory Chemokine Perspective
Chronic skin diseases and metabolic syndrome are linked by shared inflammation pathways.
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research Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration
Wnt signaling is crucial for skin, hair, and nail health and regeneration.
research Efficacy of Ozone Bagging Therapy in Equine Chronic Distal Limb Wounds: Clinical Evaluation of Eight Cases
Ozone bagging therapy effectively heals horse limb wounds.
research The systemic wrinkled skin phenotype involves aberrant expression and variation of genes related to the oxidative stress and extracellular matrix in Xiang pigs
Wrinkled skin in Xiang pigs is linked to gene changes related to oxidative stress and the extracellular matrix.
research Remolding Microenvironmental Homeostasis for Enhancing Regenerative Hypertrophic Scar Treatment Based on Functionalized Microneedles
A microneedle patch with curcumin and stem cell components effectively treats hypertrophic scars and promotes healing.
research Wnt signaling modulates mechanotransduction in the epidermis to drive hair follicle regeneration
Wnt signaling helps regenerate hair follicles by affecting how skin cells sense and respond to mechanical forces.
research Molecular Morbidity Score–Can MicroRNAs Assess the Burden of Disease?
MicroRNAs could help assess and manage multiple chronic diseases.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
research Meeting Report: 68th Montagna Symposium on the Biology of Skin “Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology”
The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.
research Primary cicatricial alopecia associated with systemic indolent mastocytosis
Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
research Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders
The immune processes causing VKH and vitiligo are similar in dogs and humans.
research Recent advances in exosomal non‐coding RNA‐based therapeutic approaches for photoaging
New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
research The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring
PBMCsec can help reduce and improve thick skin scars.
research Pathological Skin Scarring: From Mechanism to Targeted Local Therapy
Atorvastatin in a keratin hydrogel may help treat skin scars effectively.
research Mechanotransduction unifies healthy non-diabetic wound healing over time by promoting a Cd14+/C1qa+ fibroblast subpopulation
Mechanotransduction aids healthy wound healing by promoting specific fibroblasts.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research Impact of different mating and surgical protocols on the establishment of a mouse model for fetal scarless skin healing
The improved surgical method increases success and reduces fetal loss in fetal mouse models for scarless skin healing.
research Frontal Fibrosing Alopecia and the Role of Cosmeceuticals in Its Pathogenesis
Cosmeceuticals like sunscreens may trigger frontal fibrosing alopecia, but more research is needed.
research Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing
Softer hydrogels help wounds heal better with less scarring.
research Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations
Researchers found four distinct fibroblast types in human skin, which could help in treating wounds and fibrotic diseases.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research Toward understanding scarless skin wound healing and pathological scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research The Skin and Inflamm-Aging
Aging skin causes inflammation that affects the whole body.
research Targeting integrin pathways: mechanisms and advances in therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Significance of stress keratin expression in normal and diseased epithelia
Stress keratins are expressed less in diseased skin and are linked to differentiation, inflammation, and immunity.
research Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90
Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
research Combination of lyophilized adipose-derived stem cell concentrated conditioned medium and polysaccharide hydrogel in the inhibition of hypertrophic scarring
The combination of stem cell medium and hydrogel effectively reduces and improves hypertrophic scars.
research The regenerative potential of skin and the immune system
The skin's immune system helps it regenerate and fight infections.
research Furnishing Wound Repair by the Subcutaneous Fascia
The subcutaneous fascia is key to fast wound healing and could improve treatments for chronic wounds and scarring.