research Toxicity of the immune suppressant cyclosporin A in the rat
Cyclosporin A is highly toxic to rats, causing severe health issues and death.
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720-750 / 1000+ resultsresearch Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Application of Hydrogels as Three-Dimensional Bioprinting Ink for Tissue Engineering
Hydrogels are crucial for 3D bioprinting in tissue engineering.
research Incorporation of hair follicles in 3D bioprinted models of human skin
3D bioprinting can now create skin with hair-like structures for medical use.
research 3D Printing—A “Touch-Button” Approach to Manufacture Microneedles for Transdermal Drug Delivery
3D printing can make microneedles for drug delivery faster and cheaper.
research Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars
Sirtuin 1 could be a potential drug target for treating hypertrophic scars.
research Strategies for High-Efficiency Mutation Using the CRISPR/Cas System
Improving CRISPR/Cas systems can make gene editing more efficient and precise.
research Stem Cell-Derived Extracellular Vesicles: Promising Therapeutic Opportunities for Diabetic Wound Healing
Stem cell-derived vesicles show promise for healing diabetic wounds.
research Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse
Reduced plakoglobin and steroid abuse increase the risk of heart rhythm issues.
research Head and Neck 3D Bioprinting—A Review on Recent Advancements in Soft Tissue 3D Bioprinting and Medical Applications
3D bioprinting offers new ways to treat head and neck defects with bioinks that mimic natural tissues.
research The Role of Natural Hydrogels in Enhancing Wound Healing: From Biomaterials to Bioactive Therapies
Natural hydrogels can improve wound healing but face challenges in becoming widely used in clinics.
research Umbilical cord mesenchymal stem cell-derived apoptotic extracellular vesicles ameliorate cutaneous wound healing in type 2 diabetic mice via macrophage pyroptosis inhibition
Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
research The emerging roles of N6-methyladenosine (m6A) deregulation in polycystic ovary syndrome
m6A deregulation plays a key role in PCOS and could lead to new treatments.
research Efficacy of exosomes in acute kidney injury treatment and the associated mechanism (Review)
Exosomes show promise in treating acute kidney injury by protecting and repairing kidney cells.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
research Methods of keratin extraction from wool and hair and prospects of their application in biomedicine and bioengineering
Extracted keratin from wool and hair can be used in medicine and bioengineering.
research RNA Coding and Transcriptional Regulation in Skin Repair: Insights from Single-Cell Profiling and Implications for Organoid-Based Regenerative Strategies
Advances in RNA research and skin models offer hope for better skin healing without scarring.
research Adrenocortical Adenocarcinoma in a Syrian Golden Hamster ( Mesocricetus auratus) With Suspected Hyperadrenocorticism
Adrenal tumors in hamsters are rare and hard to diagnose, highlighting the need for better diagnostic tools.
research Microalgal Biofactories: Sustainable Solutions for Nutrition and Cosmetics
Microalgae can sustainably improve nutrition and cosmetics with their diverse beneficial compounds.
research XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Increasing XIAP and DDRGK1 can help prevent hearing loss from loud noise.
research The Effects of Spermidine on Functional and Transcriptomic Markers in Human Primary Keratinocytes
Spermidine may improve skin health and hair growth by enhancing cell function.
research Strength and Tenderness: Fibronectin Joins Hair Follicle Stem Cell Niche
Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
research The Impact of Excessive Sugar Consumption on Skin Health Analysis of Biological Mechanisms and Dermatological Effects
Too much sugar harms skin, causing wrinkles and acne, but a low-sugar diet can help.
research Faculty Opinions recommendation of Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions.
The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
research Genome assembly and methylome analysis of the white wax scale insect provides insight into sexual differentiation of metamorphosis in hexapod
The white wax scale insect's genome shows that complete metamorphosis evolved earlier than thought and highlights differences in male and female development.
research SAT-358 Hypercalcemia-Induced Altered Mental Status as the Primary Manifestation of Classic Hodgkin Lymphoma
An 87-year-old man showed unusual signs of Hodgkin lymphoma, primarily high calcium levels, which improved after treatment and revealed the disease.
research Rapunzel! Rapunzel! How Strong Is Your Hair?
Hair can't be as strong as Rapunzel's because it's impractical to scale up due to defects.
research Faculty Opinions recommendation of Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding.
FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
research Current advances in stem cell-based therapies for hair regeneration
Stem cell therapies show promise for hair regrowth but face production and application challenges.
research Identification of a Novel MPL Loss of Function Mutation in a Patient with Cyclic Thrombocytopenia and Characterization of This Syndrome
A new gene mutation may cause cyclic thrombocytopenia by affecting platelet production.