4 citations
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December 2013 in “The Journal of Dermatology” A new mutation in the K6b gene caused a girl's late-appearing nail condition.
74 citations
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January 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the DSG4 gene can cause a rare hair disorder similar to monilethrix.
44 citations
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August 2004 in “Journal of Investigative Dermatology” A gene deletion in DSG4 causes sparse hair in some Pakistani families.
February 2026 in “Journal of Cutaneous and Aesthetic Surgery” Ectopic acanthosis nigricans can occur at surgical sites due to skin graft mismatches.
March 2026 in “Portuguese Journal of Dermatology and Venereology” Avoid hair dye after microneedling to prevent scalp pigmentation.
58 citations
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
November 2022 in “Indian Journal of Dermatology/Indian journal of dermatology” Valproic acid can cause dark lines on nails.
74 citations
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July 1995 in “PubMed” Lowering homocyst(e)ine levels can reverse skin and hair lightening by restoring enzyme activity needed for pigmentation.
January 2025 in “Archives of Dermatological Research” 3 citations
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December 1967 in “Australasian Journal of Dermatology” Becker's Melanosis and Hypertrichosis mainly affects young males, causing brown skin patches and extra hair on one side of the upper body.
8 citations
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May 2003 in “Clinical and Experimental Dermatology” A 14-year-old girl's black hair showed unique color changes, suggesting early greying.
99 citations
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March 2013 in “Journal of Investigative Dermatology” Mutations in the ABCB6 gene cause Dyschromatosis Universalis Hereditaria.
60 citations
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October 2010 in “Molecular Imaging and Biology” Increased skin pigmentation in mice reduces bioluminescent signal accuracy.
7 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
4 citations
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March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
164 citations
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February 2010 in “Journal of Cell Science” Human dermal stem cells can become functional skin pigment cells.
2 citations
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May 2023 in “Photobiomodulation, photomedicine, and laser surgery” Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.
November 2022 in “Skin Appendage Disorders” PT-20 did not significantly improve gray hair repigmentation.
April 2023 in “International journal of dermatology and venereology” Dermoscopic features can help identify and differentiate types of pityriasis versicolor.
June 2023 in “International Journal of Dermatology” Lichen planus pigmentosus mainly affects middle-aged women with darker skin, is underreported, and is hard to treat.
Polarized microscopy helps identify hair irregularities in genetic disorders.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
2 citations
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August 2025 in “Reports — Medical Cases Images and Videos” A rare pigmented skin tumor called melanotrichoblastoma was diagnosed in a 51-year-old woman.
23 citations
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May 2017 in “Journal of the American Academy of Dermatology” FFA patients have fewer melanocytes and thinner skin compared to others.
February 2022 in “Authorea (Authorea)” PAON shows skin patterns due to genetic mosaicism.
3 citations
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January 2016 in “Dermatology online journal” Some people with lichen planus pigmentosus might later develop frontal fibrosing alopecia.
13 citations
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July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
2 citations
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November 1995 in “American Journal of Obstetrics and Gynecology” Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.
46 citations
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April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.
January 2008 in “대한피부과학회지” Micropigmentation is a safe procedure that effectively improves the appearance of scars on the scalp and eyebrows, with most patients showing excellent or good results.