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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

rTMS may help treat trichotillomania in some patients.

ETC-159 was safe up to 30 mg, but no tumor shrinkage was seen.

Vaccines and targeting TrxR variants can help prevent cancer and reduce metastasis.

Lack of KSR1 stops certain skin tumors in mice.

HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

Two specific SNPs in the TRPS1 gene cause excessive hair growth by altering the protein's structure.

Short-term treatment with ROCKi increases skin cell growth without changing stem cell features.

A new genetic mutation linked to CARASIL syndrome and small artery disease was found in a Chinese family.

The hr gene is crucial for skin and hair health, with mutations causing hair disorders.

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Human hair follicles have their own thyroid hormone system.

HVDRR is caused by VDR gene mutations, leading to vitamin D resistance, treatable with high calcium doses, but alopecia remains permanent.

Dermatologists should consider congenital syndromes like TRPS in young adults with early hair loss.

RhoA helps skin stem cells grow, aiding wound healing.

A 50 mg non-loading dose of ritlecitinib is safe for adults and adolescents.

REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.

hsa_circ_0002980 can help stop liver cancer cells from growing and spreading.

RORA may help regulate hair growth by affecting hair follicle stem cells.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

A gene mutation worsens skin irritation in mice due to a lack of certain fats.

The Hairless gene is crucial for healthy skin and hair growth.

IL-18 signaling helps mature Tregs move into the thymus.

TRH in hair follicles can influence hair color by increasing melanin.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

Trichothiodystrophy causes unusual hair and developmental issues.

A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.