research Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
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570-600 / 1000+ resultsresearch Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling
Activating Kras in mouse skin causes excess skin and hair loss.
research NF-κB Activity Is Required for Anagen Maintenance in Human Hair Follicles In Vitro
NF-κB activity is crucial for keeping hair in the growth phase.
research Ontogeny of Skin Stem Cells and Molecular Underpinnings
Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
research Efficacy and Safety of Topical 5% Azelaic Acid Solution Versus 2% Minoxidil Solution in the Treatment of Female Pattern Hair Loss
5% Azelaic acid is as effective as 2% Minoxidil for female pattern hair loss and could be an alternative for those allergic to Minoxidil or pregnant.
research EMT Factors and Metabolic Pathways in Cancer
EMT and metabolic pathways help cancer cells resist treatment and spread.
research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Sox2-positive cells determine specific hair follicle types in mammals.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
research The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
Nephronectin helps attach muscle cells to hair follicles.
research Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
research Flavonoids as Potential Wound-Healing Molecules: Emphasis on Pathways Perspective
Flavonoids can help heal wounds effectively due to their beneficial properties.
research p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis
p63 controls Satb1 to help skin develop properly.
research Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
research Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.
Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
research Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size
Caspase-3 helps control cell growth and organ size by activating YAP.
research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression
Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
research Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth
Blimp1 is crucial for hair follicle growth and skin health.
research Epidermal patterning and induction of different hair types during mouse embryonic development
Different body areas in mice produce different hair types due to interactions between skin layers.
research Molecular mechanisms of asymmetric divisions in mammary stem cells
Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
research Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer
The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
research Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
Inhibiting ornithine decarboxylase may help prevent certain skin cancers.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Sostdc1 defines the size and number of skin appendage placodes
Sostdc1 controls the size and number of hair and mammary gland structures.
research Sprouty/FGF signaling regulates the proximal–distal feather morphology and the size of dermal papillae
Sprouty and FGF balance is crucial for normal feather shape and size.
research Zfp462 deficiency causes anxiety‐like behaviors with excessive self‐grooming in mice
Zfp462 deficiency in mice causes anxiety-like behaviors and excessive self-grooming.
research Gene variants associated with acne vulgaris presentation and severity: a systematic review and meta-analysis
Certain gene variants can influence acne risk and severity.
research Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose
miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
research The Role of Exosomes Derived From Mesenchymal Stromal Cells in Dermatology
MSC-derived exosomes may help in skin repair and regeneration.
research Human epidermal neural crest stem cells as a source of Schwann cells
Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.