research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
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180-210 / 1000+ resultsresearch Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation
The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
research Can dermal delivery of therapeutics be improved using thermoresponsive nanogels?
Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
research Palmitoylethanolamide-Incorporated Elastic Nano-Liposomes for Enhanced Transdermal Delivery and Anti-Inflammation
PEA-ENL improves skin delivery and reduces inflammation without side effects.
research A folliculocentric perspective of dandruff pathogenesis: Could a troublesome condition be caused by changes to a natural secretory mechanism?
Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
research Filaggrin mutations as an archetype for understanding the pathophysiology of atopic dermatitis
Filaggrin mutations are linked to atopic dermatitis and help explain how genetics and environment affect the disease.
research Clinical Characteristics and Treatment of Acne with Sensitive Skin
Using barrier repair creams and light therapy improves acne treatment for those with sensitive skin.
research Camellia sinensis Seed Flavonoids Attenuate UVB-Induced Inflammation and UVA-Induced Photodamage via MAPK/NF-κB and AP-1 Pathways
Camellia sinensis seed flavonoids can reduce skin inflammation and damage from UV rays.
research Pesquisa e desenvolvimento de produtos cosméticos para o público masculino com óleos essenciais: caracterização da pele, eficácia clínica, perfil de consumo e influência da publicidade
Men's skincare products with essential oils can improve skin health and may increase male interest in cosmetics.
research Acne and sebaceous gland function
Effective acne treatments should reduce sebum, bacteria, and inflammation, with isotretinoin being the best for severe cases.
research Cell death by cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice
Glycerol is essential for skin hydration in mice without sebaceous glands.
research Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions
Melatonin may benefit skin health and could be a promising treatment in dermatology.
research Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration
Encapsulated stem cell exosomes in hydrogel improve wound healing.
research The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
Adam10 enzyme is crucial for healthy skin and proper Notch signaling.
research Epidermal differentiation: The role of proteases and their inhibitors
Balanced protease activity is crucial for healthy skin and hair development.
research Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing
Mutations in the ST14 gene cause skin and hair issues by disrupting important protein processing.
research Human hair follicle: reservoir function and selective targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype
Removing both KLK5 and KLK7 proteins can prevent death and skin issues in Netherton syndrome.
research Follicular and percutaneous penetration pathways of topically applied minoxidil foam
Minoxidil foam enters hair follicles and skin for hair growth.
research Genetics of Inherited Ichthyoses and Related Diseases
New genetic variants linked to inherited ichthyoses were identified, offering insights for potential gene therapy.
research Differentiation of the sebaceous gland
The exact molecular mechanisms of sebaceous gland function are still unclear.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Embryonic keratinization in vertebrates in relation to land colonization
Keratinization in embryos helped vertebrates adapt to land by forming a protective skin barrier.
research Disorders of Keratinization
Understanding genetic mutations helps diagnose and treat skin disorders like ichthyosis.
research Cushing Syndrome from Percutaneous Absorption of 1% Hydrocortisone Ointment in Netherton Syndrome
Low-potency steroids can cause serious side effects in people with skin conditions like Netherton syndrome.
research Drug Delivery with Topically Applied Nanoparticles: Science Fiction or Reality?
Nanoparticles show promise for drug delivery through hair follicles but not through healthy skin.
research Herbal nano-formulations for topical delivery
Herbal nano-formulations show potential for effective skin delivery but need more research.
research Fatty acids and related lipid mediators in the regulation of cutaneous inflammation
Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
research Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin
Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.