81 citations
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February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
70 citations
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April 2017 in “Lasers in surgery and medicine” Blue light promotes hair growth by interacting with specific receptors in hair follicles.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
51 citations
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October 2024 in “Pharmaceutics” Improving drug delivery through the skin requires understanding skin and using enhancers.
48 citations
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January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
43 citations
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November 2018 in “Nature Communications” Genetic variations affecting skin structure play a key role in severe acne.
42 citations
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January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
37 citations
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October 2021 in “Journal of Clinical Investigation” Skin inflammation can worsen intestinal inflammation and colitis.
37 citations
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April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
32 citations
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December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
32 citations
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July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
29 citations
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December 2016 in “The EMBO Journal” Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.
28 citations
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March 2019 in “Journal of Dermatological Science” The document concludes that while lab results for hair growth promotion are promising, human trials are needed and better testing methods should be developed.
22 citations
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September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
19 citations
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September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
17 citations
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February 2023 in “Cosmetics” 3D printed hollow microneedles could effectively treat skin wrinkles with fewer side effects.
9 citations
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May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
8 citations
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December 2020 in “Scientific reports” Selective breeding caused the unique curly hair in Mangalitza pigs.
7 citations
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June 2022 in “Frontiers in Medicine” ADSC-derived extracellular vesicles show promise for skin and hair regeneration and wound healing.
7 citations
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December 2020 in “ACS biomaterials science & engineering” Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.
7 citations
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October 2018 in “BMC genomics” Key genes can rewire networks, changing skin appendage types.
4 citations
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January 2021 in “Dermatologic Therapy” AI is effective in diagnosing and treating hair disorders, including detecting hair loss and scalp conditions with high accuracy, but it should supplement, not replace, doctor-patient interactions.
4 citations
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May 2020 in “PLOS ONE” Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.
4 citations
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March 2017 in “Development” Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
3 citations
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October 2021 in “Letters in Applied NanoBioScience” Nanotechnology can make cosmetics more effective for skin issues.
3 citations
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January 2019 in “Česká a slovenská farmacie” Microneedles could make it easier and less painful to deliver more types of drugs through the skin.
2 citations
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May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
2 citations
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January 2022 in “BioMed Research International” LED light therapy at 863 nm wavelength can slow down skin tumor growth and reduce inflammation in mice.
2 citations
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June 2020 in “Journal of Investigative Dermatology” 3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.
1 citations
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June 2024 in “Revista Colombiana de Endocrinología Diabetes & Metabolismo” The risks of testosterone implants in women outweigh the benefits.