April 2026 in “Journal of Pharmaceutical Innovation” Curcumin nanocrystal gel improves skin absorption and is safe and effective for topical use.
4 citations
,
March 2023 in “Journal of controlled release” A special gel with medicine helps prevent melanoma from coming back after surgery.
1 citations
,
November 2024 in “Journal of Cutaneous and Aesthetic Surgery” This treatment effectively reduces dark circles by improving volume and skin quality.
December 2025 in “Scientific Reports” α-Mangostin can naturally lighten skin by reducing melanin.
April 2024 in “The Indonesian Biomedical Journal” Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
6 citations
,
January 2018 in “Advances in experimental medicine and biology” Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
10 citations
,
April 2008 Chitin nanofibrils can improve skin health and help deliver active ingredients into the skin.
Encapsulating curcumin in nanoparticles improves its stability, release, and absorption in the body.
11 citations
,
August 2006 in “Cell Biology International” Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.
1 citations
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January 1981 in “Elsevier eBooks” Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
October 2025 in “Pharmaceutics” Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
December 2023 in “Melatonin research” Nanocarriers make melatonin more effective and reduce side effects.
March 2024 in “Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān/Majallah-i taḥqīqāt-i ̒ulūm-i pizishkī-i Zāhidān./Zahedan journal of researches in medical sciences” Microneedling with PRP effectively reduces facial pigmentation with minimal side effects.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
2 citations
,
February 2023 in “Research Square (Research Square)” The scaffold effectively prevents melanoma relapse and aids wound healing.
1 citations
,
January 2014 in “Aesthetic Plastic Surgery” Tattooing improves appearance of scalp alopecia and scars.
13 citations
,
March 2020 in “Frontiers in cell and developmental biology” A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
5 citations
,
January 2012 in “Journal of Tissue Science & Engineering” Collagen membranes improve melanocyte growth for treating skin depigmentation.
January 2013 in “วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)” Safflower extract increases melanin production in certain skin cells without harming them.
January 2019 in “Springer eBooks” PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.
Delonix polymeric nanoparticles with isotretinoin effectively treat acne by targeting hair follicles and reducing skin irritation.
2 citations
,
September 2024 in “Animals” Key genes influence melanin in chicken muscles, affecting their value.
1 citations
,
November 2024 in “Life” Desmodesmus pannonicus water extract may help reduce skin pigmentation, heal wounds, and promote hair growth.
18 citations
,
January 2021 in “Theranostics” The targeted nanohybrids effectively reduced psoriasis symptoms and improved skin health.
December 2025 in “Biomedicine & Pharmacotherapy” Melamax® protects skin from UV damage and reduces inflammation and oxidative stress.
297 citations
,
December 2005 in “Journal of controlled release” P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
15 citations
,
April 2021 in “International Journal of Pharmaceutics” Smaller mesoporous nanoparticles can improve the effectiveness of topical drugs by penetrating skin furrows.
January 2024 in “International Journal of Herbal Medicine” Melanin is important for hair color, health, and UV protection.
20 citations
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April 2020 in “Journal of advanced Biomedical and Pharmaceutical Sciences” Niosomal methylene blue gel effectively improves moderate to severe acne.