research FASCE, the benefit of spironolactone for treating acne in adult females: study protocol for a randomized double-blind trial
Spironolactone is a promising alternative to antibiotics for treating acne in adult females.
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research Ethinylestradiol/Chlormadinone Acetate for Use in Dermatological Disorders
Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.
research The influence of Castanea sativa Mill. flower extract on hormonally and chemically induced prostate cancer in a rat model
Chestnut flower extract may help reduce prostate cancer growth.
research Development and efficacy evaluation of hair care formulations containing vegetable oils and silicone
Olive and Brazil nut oils improve hair strength, shine, and softness better than silicone.
research Somatotropin Penetration Testing from Formulations Applied Topically to the Skin
The new topical growth hormone formula has high skin penetration and bioavailability.
research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research METABOLISM OF DEHYDROEPIANDROSTERONE BY ISOLATED HUMAN HAIR FOLLICLES
Human hair follicles can process steroid hormones like DHEA.
research 569 Application of 3D scaffold free dermal spheroids to investigate retinol and retinol alternatives mechanism of action on extracellular matrix
research FASCE, benefit of spironolactone for treating acne of adult female: study protocol for a randomized double-blind trial
Spironolactone may be a better acne treatment for adult women than antibiotics.
research Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Follicular-targeted delivery of spironolactone provided by polymeric nanoparticles
Nanoparticles can effectively deliver spironolactone to hair follicles for treating alopecia and acne.
research Single hair fiber assessment techniques to discriminate between mineral oil and coconut oil effect on hair physical properties
Coconut oil makes hair stronger and more flexible than mineral oil.
research 42752 Evaluation of Eyebrow and Eyelash Regrowth and Patient Satisfaction in the Phase 3 THRIVE-AA1 Trial with CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata
CTP-543 significantly improved eyebrow and eyelash regrowth and patient satisfaction in adults with alopecia areata.
research PLASMA C19 STEROID SULPHATE LEVELS AND INDICES OF ANDROGEN BIOAVAILABILITY IN FEMALE PATTERN ANDROGENIC ALOPECIA
Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
research Alopecia in Rats Fed Certain Soybean Oil Meal Rations.
Rats fed soybean oil meal lost hair, but adding inositol, biotin, cystine, or methionine to their diet prevented this and improved growth.
research Pure linoleate deficiency in the rat: influence on growth, accumulation of n-6 polyunsaturates, and [1-14C]linoleate oxidation
Linoleate deficiency in rats reduces growth and n-6 polyunsaturate accumulation, causing mild symptoms.
research Activation of Fibroblast and Papilla Cells by Glycolipid Biosurfactants, Mannosylerythritol Lipids.
MEL-A from soybean oil can boost fibroblast and papilla cells, potentially aiding hair growth.
research Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
research Efficacy and tolerance of 2,3-diphenylcyclopropenone in propylene glycol versus 2,3-diphenylcyclopropenone in isopropanol – a novel formula designed for the treatment of alopecia areata
Both treatments helped hair regrowth in alopecia areata, with isopropanol being better tolerated.
research Lipid Profile and 5α-Reductase Inhibition Activity of Proprietary Ultrahigh-Pressure Supercritical Carbon Dioxide and Hexane Saw Palmetto Extracts
UHP-sCESr is as effective as HESr for treating BPH symptoms.
research Suprabasal change and subsequent formation of disulfide-stabilized homo- and hetero-dimers of keratins during esophageal epithelial differentiation
Keratins K4 and K13 form stable dimers in mature esophageal cells, aiding cell stability.
research A disease-causing novel missense mutation in the ST14 gene underlies autosomal recessive ichthyosis with hypotrichosis syndrome in a consanguineous family
A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.
research Preparation of human hair keratin/calcium alginate blend films
More human hair protein makes the films weaker and less clear.
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research No effects of statins on improvement of alopecia areata: a four year retrospective cohort study in a metropolitan area
Statins do not help improve alopecia areata.
research Banding Pattern on Polarized Hair Microscopic Examination and Unilateral Polymicrogyria in a Patient With Steroid Sulfatase Deficiency
A patient with steroid sulfatase deficiency had a unique hair pattern and a brain malformation not previously linked to the condition.
research The acyl-CoA binding protein is required for normal epidermal barrier function in mice
ACBP is crucial for healthy skin in mice.
research Analysis of heterogeneous reaction between reducing agents and keratin fibers using Raman spectroscopy and microspectrophotometry
The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.
research 439 Gradients of Mesenchymal Stiffness Control Sweat Gland Cell Fate Specification During Morphogenesis
Mesenchymal stiffness affects sweat gland cell development.
research Sterile matrix grafting for onycholysis in the setting of valproic acid use
Surgical grafting may fix nail issues caused by valproic acid.