research Defining the identity of mouse embryonic dermal fibroblasts
Researchers identified specific genes that are important for mouse skin cell development and healing.
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research Reviewer #2 (Public Review): Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
research Obesity and peri-implantation endometrium
Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.
research SCA-1+ Cells with an Adipocyte Phenotype in Neonatal Mouse Skin
Sca-1+ cells in newborn mouse skin may become fat cells.
research Extracellular Vesicles Including Exosomes for Hair Follicle Regeneration
Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.
research Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective
Controlling cellular changes can enable safe rejuvenation without cancer risk.
research A preview of selected articles
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
research DPSCs and SHED in Tissue Engineering and Regenerative Medicine
DPSCs and SHED have great potential for medical treatments and tissue repair.
research Touch Receptors Undergo Rapid Remodeling in Healthy Skin
Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.
research Hair Follicle Organoids Using Human iPSC-Derived Ectodermal Precursor Cells for Hair Regenerative Medicine
Human stem cells can help grow hair for regenerative medicine.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Dissecting the bulge in hair regeneration
Stem cells in hair follicles are diverse and change throughout the hair cycle.
research Current application of tissue-engineered dermal scaffolds mimicking the extracellular matrix microenvironment in wound healing
Tissue-engineered scaffolds help heal difficult wounds by supporting cell growth and repair.
research Regulation of adipocyte dedifferentiation at the skin wound edge
Adipocytes can change into fibroblast-like cells to help with wound healing.
research Transdifferentiation of corneal epithelium into epidermis occurs by means of a multistep process triggered by dermal developmental signals
Corneal cells can transform into skin and hair cells through specific signals.
research States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility
Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.
research Regenerative Therapies for Cosmetic Dermatology for Patients with Diabetes Mellitus: Skin Aging, Aesthetic Concerns, and Evidence-Based Best Practices
A diabetes-informed approach is essential for safe and effective skin rejuvenation treatments in diabetics.
research Co-expression of PADI isoforms during progenitor differentiation enables functional diversity
Different PADI isoforms help cells develop diverse functions.
research Malignant Melanoma and Its Stromal Nonimmune Microecosystem
The surrounding tissue plays a crucial role in the growth and spread of skin cancer.
research The origins of skin diversity: lessons from dermal fibroblasts
New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.
research NG2 Proteoglycan Expression in Mouse Skin: Altered Postnatal Skin Development in the NG2 Null Mouse
NG2 is crucial for normal skin and hair development in mice.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors (SKP) by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Epidermal and Hair Follicle Progenitor Cells Express Melanoma-Associated Chondroitin Sulfate Proteoglycan Core Protein
MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
research Biomaterial-based mechanical regulation facilitates scarless wound healing with functional skin appendage regeneration
Biomaterials can help heal wounds without scars and regenerate skin features.
research Exosomes: A Promising Strategy for Repair, Regeneration and Treatment of Skin Disorders
Exosomes could be a promising way to help repair skin and treat skin disorders.
research Androgens in cervical cancer: Their role in epidemiology and biology
Androgens increase cervical cancer risk and affect its development.
research Lactate in skin homeostasis: metabolism, skin barrier, and immunomodulation
Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.
research Comparative gene expression analysis of nestin-expressing hair follicle-derived cells
Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.
research Fibroblast heterogeneity: implications for human disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.