October 2025 in “Frontiers in Pharmacology” Arctium lappa L. might help treat immune-related skin diseases, but more research is needed.
Oral Minoxidil can cause serious eye problems, but stopping it can improve vision.
January 2023 in “Hormone and Metabolic Research” Existing drugs are being repurposed to treat cardiometabolic disorders, which is safer, faster, and cheaper than developing new drugs.
September 2022 in “Dermatology and therapy” Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.
July 2015 in “Egyptian Journal of Dermatology and Venereology” People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.
10 citations
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August 2021 in “EMBO Reports” The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
6 citations
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December 1987 in “Mayo Clinic proceedings” Retinoids are effective for severe acne and psoriasis but can cause serious side effects and birth defects.
June 2023 in “Frontiers in Cardiovascular Medicine” Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
50 citations
,
January 2013 in “Indian Journal of Dermatology” Some skin conditions, like psoriasis and early-onset baldness, may indicate metabolic syndrome, and others are linked to diabetes risk and cardiovascular issues.
559 citations
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October 2020 in “Frontiers in Molecular Biosciences” Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.
245 citations
,
January 2010 in “Blood” Antihepcidin antibodies may treat inflammation-induced anemia by improving iron metabolism.
146 citations
,
September 2013 in “Advances in nutrition” Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.
137 citations
,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
132 citations
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September 2021 in “Frontiers in Public Health” COVID-19 affects multiple body systems, not just the lungs.
90 citations
,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
86 citations
,
August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
76 citations
,
January 2022 in “Journal of Tissue Engineering” Microneedle patches could replace injections but need more development for better use in medicine.
61 citations
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June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
55 citations
,
April 2022 in “Frontiers in Immunology” Cholesterol affects coronavirus spread and could be a target for treatment.
45 citations
,
May 2024 in “International Journal of Molecular Sciences” Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
44 citations
,
September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
42 citations
,
August 2013 in “International Journal of Women's Health” Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
36 citations
,
December 2021 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.
35 citations
,
January 2024 in “BioMolecular Concepts” Lifestyle changes, exercise, and antioxidants can help manage polycystic ovary syndrome.
29 citations
,
October 2019 in “Journal of dermatological science” Studying premature aging syndromes helps understand human aging and suggests potential treatments.
26 citations
,
June 2024 in “Frontiers in Immunology” SOCS1 and SOCS3 help control skin inflammation and are important for developing treatments for skin diseases.
24 citations
,
May 2022 in “Frontiers in Endocrinology” Activating brown fat may help manage PCOS symptoms.
23 citations
,
September 2021 in “Frontiers in Cellular and Infection Microbiology” Testosterone's effects on COVID-19 are unclear and need more research.
20 citations
,
November 2019 in “International Journal of Environmental Research and Public Health” Breathing in high levels of certain air pollutants significantly increases women's risk of developing Polycystic Ovary Syndrome.
15 citations
,
December 2021 in “Pharmaceutics” The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.