research Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
Spaceflight can harm skin health by altering gene expression, affecting DNA, mitochondria, and skin barriers.
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research REV7: a small but mighty regulator of genome maintenance and cancer development
REV7 is crucial for genome stability and cancer treatment, making it a potential target for therapy.
research Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche
Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
research Immunosenescence and inflammaging in Parkinson’s disease: mechanisms and therapeutic prospects
Age-related immune changes worsen Parkinson's disease, suggesting new treatment strategies.
research Advances In Mesenchymal Cell Therapy In Dermatology And Aesthetic Medicine
Mesenchymal stem cells improve skin appearance and structure in dermatology and aesthetic medicine.
research A Short Report on Melanocyte/Melanoma Culture, Senescence, and Reproducibility
Clear documentation and shared best practices are essential for improving research consistency in pigment cells.
research Natural Compounds Targeting MAPK, PI3K/Akt, and JAK/STAT Signaling in Papillary Thyroid Cancer
Natural compounds may help treat advanced papillary thyroid cancer by targeting specific molecular pathways.
research Detection of the nuclear translocation of androgen receptor using quantitative and automatic cell imaging analysis
A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.
research Senotherapeutic Potential of Araliadiol in Senescent Human Dermal Fibroblasts: An In Vitro Study Using Three Senescence Models
Araliadiol may help reduce skin aging and inflammation without killing cells.
research Integrated analysis of long non-coding RNA and mRNA expression in different colored skin of koi carp
lncRNAs significantly influence koi carp skin color.
research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.
research The Hairless Phenotype of the Hirosaki Hairless Rat Is Due to the Deletion of an 80-kb Genomic DNA Containing Five Basic Keratin Genes
Hirosaki hairless rats lack hair due to missing DNA with key keratin genes.
research Extracellular vesicles in age-related diseases: disease pathogenesis, intervention, and biomarker
Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
research The Roles of EDA2R in Ageing and Disease
EDA2R is a key gene linked to ageing and diseases, and targeting it may help treat conditions like hair loss and chronic diseases.
research Application of mesenchymal stem cells for anti-senescence and clinical challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Therapeutic Efficacy and Promise of Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles in Aging and Age-Related Disorders
Human umbilical cord stem cell vesicles may help treat aging and related diseases.
research A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies
Personalized skin rejuvenation using genomics shows promise but needs more research.
research Genome assembly and methylome analysis of the white wax scale insect provides insight into sexual differentiation of metamorphosis in hexapod
The white wax scale insect's genome shows that complete metamorphosis evolved earlier than thought and highlights differences in male and female development.
research Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
TNFα helps grow and maintain liver cells in 3D culture for a long time.
research The emerging role of cellular senescence in amyotrophic lateral sclerosis
Cellular senescence may play a role in ALS, and anti-senescence therapies could be a promising treatment.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Plasticity of epithelial stem cells in tissue regeneration
Epithelial stem cells can adapt and help in tissue repair and regeneration.
research Flavonoids as Potential Wound-Healing Molecules: Emphasis on Pathways Perspective
Flavonoids can help heal wounds effectively due to their beneficial properties.
research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
research Recent advances in Forensic DNA Phenotyping of appearance, ancestry and age
Forensic DNA Phenotyping can now better predict appearance, ancestry, and age from DNA, but more research is needed for precise police use.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research Multifaceted role of keratins in epithelial cell differentiation and transformation
research A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus
Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
research Keratin intermediate filaments in the colon: guardians of epithelial homeostasis
Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
research Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells
Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.