research Fertility and sexual life of men after their forties and in older age.
Men's fertility and sexual health decline with age, with reduced testosterone and virility, and many lose fertility by their eighties.
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900-930 / 1000+ resultsresearch Harm reduction measures in a recreational gym user with anabolic androgenic steroid dependence: a case report in the context of current best clinical practice
Non-medical steroid use in gym-goers is risky and needs better prevention and care strategies.
research The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin
DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
research Visualising Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Myotonic Dystrophy—A Progeroid Disease?
Myotonic dystrophy may be classified as a segmental progeroid disorder.
research Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and interfollicular keratinocytes
research The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A
Low-dose bisphenol A increases prostate size in rats by affecting certain enzymes.
research Fluorine-Induced Apoptosis and Lipid Peroxidation in Human Hair Follicles In Vitro
research Hirsutism
research Multiple cell types guided by neurocytes orchestrate horn bud initiation in dairy goats
Nerve cells and other cell types work together to start horn growth in dairy goats.
research LHX2: a transcription factor in development, homeostasis, repair, and disease
LHX2 is crucial for development, tissue repair, and preventing diseases.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Referee report. For: Exploring the use of phytotherapy in benign prostatic hyperplasia [BPH]: a systematic review [version 1; peer review: 2 approved with reservations]
Plant-based treatments may help reduce BPH symptoms, but more research is needed.
research Anti-Müllerian Hormone and Polycystic Ovary Syndrome in Women and Its Male Equivalent
High AMH levels are linked to PCOS in women and may have a male equivalent with similar traits.
research Einfluss von Melatonin auf die Physiologie des Haares
research Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants
Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.
research Cytotoxic and antioxidant effect of the ethanolic extract of Citrullus colocynthis L. plant fruit
Citrullus colocynthis fruit extract has strong antioxidant and cancer-fighting potential.
research Understanding the Secular Decline in Testosterone: Mechanisms, Consequences, and Clinical Perspectives
Lifestyle changes and environmental strategies can help address declining testosterone levels.
research SUN-207 Hot Flashes, Flushing, and Sweating in a Middle-Aged Man with Pituitary Macroadenoma
Middle-aged men with unusual hot flashes should be checked for pituitary tumors.
research Notes from the Editor Emeritus: Coincidental Epigenetics or Post-Finasteride Syndrome (PFS)?
The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.
research Morphology of the testis and the epididymis in rats with dihydrotestosterone (DHT) deficiency.
DHT deficiency in rats reduces sperm content and affects testis structure over time.
research An adolescent girl presenting with primary amenorrhea: A case report of complete androgen insensitivity syndrome
A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
research Vaccines, adjuvants and autoimmunity
Vaccines are generally safe, but rare autoimmune reactions can occur, often influenced by genetics.
research Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis
Oral testosterone therapy raises heart risk more than other methods.
research Clinical biochemistry of dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring
Curcumin can protect against mercury's harmful effects on brain and behavior.
research Systematic analyses of murine masculinization processes based on genital sex differentiation parameters
DHT is crucial for urethral formation, and its disruption can affect masculinization and lead to hypospadias.
research Are sex hormones promising candidates to explain sex disparities in the COVID-19 pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor
TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.