252 citations
,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
77 citations
,
July 2020 in “Journal of the European Academy of Dermatology and Venereology” Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
16 citations
,
March 2025 in “International Journal of Molecular Sciences” Extracellular vesicles show promise in skin treatments but need more research and standardization.
10 citations
,
August 2024 in “Clinical Cosmetic and Investigational Dermatology” Natural ingredients may help reduce skin aging by protecting cells and boosting collagen.
8 citations
,
July 2024 in “Cells” PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
January 2024 in “Journal of tissue engineering” Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
March 2026 in “International Journal of Science and Research (IJSR)” Melatonin protects skin and supports hair growth.
September 2009 in “Dermato-endocrinology” Good nutrition and vitamins are important for healthy skin and can prevent diseases.
36 citations
,
October 2015 in “Journal of Cosmetic Dermatology” The serum improved skin aging signs by enhancing cell metabolism and reducing wrinkles.
9 citations
,
September 2018 in “Journal of Photochemistry and Photobiology B-biology” A hair-growth formula with cystine and thiamin helps protect skin cells against UV damage and improves their growth.
120 citations
,
February 2009 in “Apoptosis” Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
86 citations
,
October 2017 in “Clinics in Dermatology” Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
December 2025 in “Journal of Advanced Biotechnology and Experimental Therapeutics” Mesenchymal stem cells may help reduce melanin in UV-exposed mice.
6 citations
,
February 1974 in “The BMJ” The document concludes that scalp disorders can be treated with hair washing, specific shampoos, medications, and sometimes surgery or hair transplants, but hereditary baldness is untreatable.
87 citations
,
July 2007 in “British Journal Of Nutrition” Lactococcus lactis strain H61 may reduce some ageing symptoms.
21 citations
,
July 2017 in “Journal of Cosmetic and Laser Therapy” Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
1 citations
,
October 2025 in “International Journal of Nanomedicine” Exosomes could revolutionize skin disease treatment and healing.
May 2026 in “Commagene Journal of Biology” Anti-aging peptides can improve skin appearance but need better delivery methods and more research.
22 citations
,
November 2024 in “Planta” Aromatic plants can naturally help prevent skin aging and improve skin health.
11 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
10 citations
,
May 2024 in “npj Regenerative Medicine” Umbilical cord cells may help delay skin aging.
122 citations
,
April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
114 citations
,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
20 citations
,
February 2017 in “International Journal of Dermatology” Honokiol helps protect skin from damage and aging caused by cigarette smoke.
10 citations
,
August 2020 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” Hyaluronic acid filler injections are a favored non-surgical method to improve facial aging signs due to their convenience, effectiveness, and durability.
9 citations
,
January 2016 in “Skin Pharmacology and Physiology” The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
7 citations
,
March 2025 in “Free Radical Biology and Medicine” Imbalanced redox dynamics cause skin aging by damaging fibroblasts and stem cells.
Folate salts penetrate skin well and improve wound healing, suggesting potential for skin treatments.
April 2026 in “International Journal of Molecular Sciences” Diabetic patients need tailored cosmetic treatments for skin aging, with new therapies showing promise.