December 2025 in “FEBS Open Bio” Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
October 2025 in “Bioengineering” Coating surgical meshes with PRP may improve hernia repair outcomes.
June 2025 in “Problems of Cryobiology and Cryomedicine” Low temperatures don't harm hyaluronic acid's healing abilities.
May 2025 in “Journal of International Medical Research” Micrografting may improve healing and hair growth, but more research is needed.
May 2023 in “Journal of Investigative Dermatology” Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
May 2025 in “The Open Biomedical Engineering Journal” Adipose tissue and PRP together improve healing and surgery outcomes but need more research for consistent use.
9 citations
,
February 2021 in “Frontiers in Cell and Developmental Biology” Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.
97 citations
,
May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
51 citations
,
October 2024 in “Pharmaceutics” Improving drug delivery through the skin requires understanding skin and using enhancers.
30 citations
,
May 2019 in “Medicinal Research Reviews” Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
19 citations
,
October 2023 in “Bioengineering” tSVF is effective for treating inflammation-related conditions, with centrifugation being the best method for isolation.
15 citations
,
August 2023 in “Journal of Nanobiotechnology” Nanotechnology could improve scar treatment but needs more development.
9 citations
,
March 2019 in “Molecular & cellular proteomics” Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
6 citations
,
March 2024 in “Experimental Dermatology” Fibrosis causes loss of important fat cells, affecting tissue function.
6 citations
,
April 2023 in “Cosmetics” Exosomes could be effective for improving skin health and treating skin diseases.
4 citations
,
May 2025 in “Life” 3D bioprinting shows promise for better skin regeneration by creating structures similar to natural skin.
4 citations
,
January 2022 in “BioMed Research International” Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.
3 citations
,
February 2025 in “Frontiers in Cell and Developmental Biology” Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.
3 citations
,
January 2024 in “Cell Transplantation” Combining platelet concentrates with stem cells improves regenerative therapies.
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.
August 2025 in “MedComm – Biomaterials and Applications” Liposomal delivery systems improve drug absorption through the skin, offering potential for better treatments.
December 2023 in “Regenerative therapy” miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
28 citations
,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
22 citations
,
December 2013 in “Stem cells and development” Horse skin stem cells combined with platelet-rich plasma improve skin healing.
20 citations
,
November 2021 in “Biomedicines” Adipose-derived stem cells show promise in treatments but need more research for safety, especially in cancer.
March 2026 in “Preprints.org” The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
November 2025 in “International Journal of Molecular Sciences” PRP shows promise in healing and regeneration but needs standardized protocols for consistent results.
47 citations
,
November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
75 citations
,
January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.