81 citations
,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
56 citations
,
November 2022 in “Biomolecules” Targeting macrophages may improve wound healing.
46 citations
,
October 2018 in “Neuroscience Bulletin” 41 citations
,
July 2019 in “Clinical Cosmetic and Investigational Dermatology” The skin's immune system helps it regenerate and fight infections.
37 citations
,
February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
37 citations
,
May 2021 in “Frontiers in Cell and Developmental Biology” Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
36 citations
,
January 2017 in “Stem Cells International” A special stem cell fluid can speed up wound healing and hair growth in mice.
35 citations
,
February 2023 in “Biomolecules” Granzyme B is important in autoimmune skin diseases and could be a new treatment target.
33 citations
,
February 2024 in “International Journal of Molecular Sciences” Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
31 citations
,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
23 citations
,
January 2024 in “Journal of Investigative Dermatology” Corticosteroids can reduce scarring in acne keloidalis by targeting specific cells.
20 citations
,
August 2022 in “Frontiers in Immunology” Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
19 citations
,
October 2023 in “Bioengineering” tSVF is effective for treating inflammation-related conditions, with centrifugation being the best method for isolation.
18 citations
,
February 2024 in “ACS Polymers Au” Silk fibroin shows promise for wound care but faces challenges in becoming widely available.
18 citations
,
January 2009 in “Experimental Dermatology” mTOR may link different pathways in hair follicle tumor formation.
15 citations
,
May 2022 in “Journal of Investigative Dermatology” Endothelial TLR2 is crucial for timely wound healing, but HFSC TLR2 is not needed.
11 citations
,
February 2019 in “Stem cells international” Skin-derived stem cells grow faster and are easier to obtain than hair follicle stem cells, but both can become various cell types.
11 citations
,
February 2018 in “Oncotarget” Lower SMAD2/3 activation predicts more severe skin cancer.
8 citations
,
August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
8 citations
,
November 2024 in “EMBO Molecular Medicine” Targeting JAK-STAT1 can reduce inflammation and promote hair growth in conditions linked to EGFR deficiency.
5 citations
,
November 2024 in “Advanced Science” A new culture system can grow tooth-like structures from dental cells but can't yet develop roots.
5 citations
,
January 2023 in “Cell proliferation” Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
4 citations
,
January 2022 in “Life” Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.
2 citations
,
September 2022 in “Frontiers in Immunology” T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
1 citations
,
April 2025 in “Journal of Clinical Medicine” Hair loss in alopecia areata can negatively affect sexual quality of life.
1 citations
,
January 2024 in “Fibrosis” Hydrogels show promise for scarless wound healing by reducing skin fibrosis.
1 citations
,
December 2022 in “BMC Plant Biology” The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.
1 citations
,
October 2022 in “Journal of food and nutrition research” Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).
1 citations
,
April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
Reprogramming adult fibroblasts may enable scar-free healing.