18 citations
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March 2015 in “Journal of Investigative Dermatology” Silencing certain circadian clock genes increases skin pigmentation.
14 citations
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December 2021 in “International journal of molecular sciences” Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.
11 citations
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April 2023 in “Skin Health and Disease” Psychological stress can worsen skin conditions like psoriasis and acne.
7 citations
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May 2022 in “Frontiers in Medicine” Combining camouflage with psychotherapy improves quality of life for vitiligo patients.
Trilostane generally improved symptoms in dogs with Cushing's syndrome, but dosage adjustments were needed over time.
January 2025 in “Case Reports in Endocrinology” Accurate diagnosis of rare hyperandrogenism conditions requires detailed testing and sometimes invasive procedures.
February 2024 in “Animals” Most dogs with adrenal-dependent hypercortisolism had normal blood pressure after one year of treatment or surgery.
March 2026 in “JCEM Case Reports” Surgery removed ovarian tumors, normalizing testosterone and improving symptoms.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
289 citations
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May 2003 in “Journal of Investigative Dermatology” Human skin can produce steroids from cholesterol.
156 citations
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August 2014 in “Cochrane library” Budesonide is not effective for maintaining remission in Crohn's disease beyond three months.
137 citations
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January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
72 citations
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July 2022 in “Frontiers in Systems Biology” Modern lifestyles harm beneficial microbes, affecting health.
59 citations
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August 2004 in “Human Reproduction Update” Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
26 citations
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July 2012 in “Endocrine Connections” Mitotane changes steroid breakdown, affecting cortisol availability.
23 citations
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January 2016 in “Brazilian Journal of Psychiatry” First-episode psychosis patients have higher hair cortisol levels, indicating early stress response issues.
21 citations
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January 2020 in “Conservation Physiology” Hair follicles increase hair cortisol levels, so consistent hair collection methods are important.
21 citations
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February 2015 in “Clinical Cosmetic and Investigational Dermatology” Keloids may be influenced by stress and psychological factors.
15 citations
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April 2017 in “Hormones” Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
15 citations
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January 2017 in “Pigment International” Early hair graying is often inherited and influenced by genetics, environment, and lifestyle, but treatment options are limited.
15 citations
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April 2016 in “Hormones” Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
8 citations
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December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
6 citations
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October 1998 in “Journal of endocrinological investigation” Antiandrogens help manage PCOS symptoms but need careful monitoring.
4 citations
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July 2022 in “The Journal of Clinical Endocrinology & Metabolism” A specific genetic mutation causes POMC deficiency, leading to symptoms like weight gain and red hair.
3 citations
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June 2024 in “International Journal of Molecular Sciences” Prolactin affects skin health and may lead to new treatments for skin and hair issues.
2 citations
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September 2022 in “Frontiers in Immunology” T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
2 citations
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January 2014 in “Journal of Integrated Health Sciences” Obesity is strongly linked to the severity of hirsutism in women.
2 citations
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January 2017 in “Case reports in endocrinology” Ashwagandha root improved symptoms of nonclassic 11-hydroxylase deficiency in an elderly woman.
1 citations
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February 2023 in “Applied sciences” The new topical growth hormone formula has high skin penetration and bioavailability.
1 citations
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September 2015 in “Pathology - Research and Practice” Stress during pregnancy can thin fetal skin.