research Experimental Production of Cutaneous Calcinosis and Sclerosis with Dihydrotachysterol (AT-10) 1
Giving dihydrotachysterol to mother rats caused skin hardening and bone issues in their babies through milk.
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research Farmácia Aliança - Maia
Dutasteride is more effective than finasteride for hair growth, and sublingual apomorphine quickly improves Parkinson's symptoms.
research Prostate cancer and androgenic alopecia: The role of finasteride as a dual agent
Finasteride treats hair loss and reduces prostate cancer risk.
research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Increased expression of PD‐L1 and PD‐L2 in dermal fibroblasts from alopecia areata mice
PD‐L1 and PD‐L2 may not effectively control immune activation in alopecia areata.
research FORMULATION AND EVALUATION OF TRIAMCINOLONE ACETONIDE SERUM WITH DERMA STAMP ASSISTED DELIVERY FOR THE MANAGEMENT OF ALOPECIA AREATA
The serum with microneedling device improves hair loss treatment effectively and safely.
research Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride
Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
research Crystallization Engineering in Aza-Steroid: Application in the Development of Finasteride
A new method was developed to purify finasteride for better medical use.
research FORMULATION AND EVALUATION OF TRIAMCINOLONE ACETONIDE SERUM WITH DERMA STAMP ASSISTED DELIVERY FOR THE MANAGEMENT OF ALOPECIA AREATA
The serum with microneedling effectively treats alopecia areata by enhancing drug delivery and is safe and patient-friendly.
research Alopesia Areata Dengan Pengobatan Triamcinolone Acetonide
Alopecia areata is the most common type of baldness treated with corticosteroids and minoxidil.
research COMPARATIVE EFFICACY OF TOPICAL CLOBETASOL PROPIONATE 0.05% OINTMENT AND TOPICAL TACROLIMUS 0.1% OINTMENT IN THE TREATMENT OF ALOPECIA AREATA
Clobetasol propionate 0.05% ointment is more effective than tacrolimus 0.1% ointment for treating alopecia areata.
research Retinoic acid drives hair follicle stem cell activation via Wnt/β‐catenin signalling in androgenetic alopecia
Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
research Drugs in Dermatology Finasteride in androgenic alopecia
research Recovery of resistant alopecia areata treated with tofacitinib: An 8-year-old child's case report
Tofacitinib helped an 8-year-old child recover from a type of hair loss that is hard to treat.
research Histopathological characterization of inflammatory interparietal involvement in frontal fibrosing alopecia
FFA and FAPD might be related or stages of the same disease.
research Combined Low Dose Oral Minoxidil and Immunomodulator Efficacy and Safety in Alopecia Areata: A Systematic Review
Combining low-dose oral minoxidil with immunomodulators shows promise for treating alopecia areata but needs more research.
research Localized Acquired Perforating Dermatosis on Scalp Presented With Acute and Diffuse Total Alopecia
Treatment improved scalp conditions and hair loss with no recurrence after 1 year.
research Early postnatal neuroactive steroid manipulation differentially affects recognition memory and passive avoidance performance in male rats
Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.
research Evaluation of the Efficacy and Safety of Oral Tofacitinib for the Treatment of Alopecia Areata in Children
Tofacitinib effectively reduces hair loss in children with alopecia areata but may cause mild side effects and relapses.
research Comparison of Efficacy of Oral Tofacitinib Versus Oral Minoxidil in Patients with Alopecia Areata
Oral tofacitinib is more effective than oral minoxidil for treating alopecia areata.
research Tralokinumab as a therapeutic option for patients with concurrent atopic dermatitis and alopecia areata
Tralokinumab may help improve symptoms of atopic dermatitis and alopecia areata.
research Activity‐based therapeutic algorithm for folliculitis decalvans: A practical tool for effective management
A new treatment plan helps manage folliculitis decalvans effectively.
research Estudo comparativo do óleo de cedro e do óleo de rícino associados à alta frequência no tratamento da alopecia androgenética
Cedar and castor oils with high frequency can help hair growth in androgenetic alopecia.
research Ritlecitinib: Efficacy of a Novel Therapy for Severe Alopecia Areata in Patients Aged 12 Years and Older
Ritlecitinib is effective and safe for treating severe alopecia areata in people aged 12 and older.
research Updated Integrated Safety Analysis of Ritlecitinib Over 72 Months In Patients With Alopecia Areata From the ALLEGRO Clinical Trial Program
Ritlecitinib is generally safe for alopecia areata patients over 72 months.
research Ritlecitinib for the Management of Alopecia Areata: A Narrative Review of Real-World Evidence and Selected Post Hoc Analyses
Ritlecitinib, a JAK3 and TEC kinase inhibitor, shows promise as an effective treatment for alopecia areata (AA), demonstrating significant hair regrowth and reduced disease severity in both clinical trials and real-world studies. The ALLEGRO phase 2b/3 trial with 522 patients highlighted its efficacy, although prior treatments like corticosteroids influenced early responses. Real-world evidence from Italy and China supports its effectiveness, especially in JAK inhibitor-naïve patients, with mild adverse events reported. Studies in adolescents and children also showed significant improvements. However, the literature is limited and heterogeneous, necessitating larger, long-term studies to confirm its long-term safety and effectiveness, particularly in diverse and pediatric populations.
research Antihormonal properties of some new A-homo-B, 19-dinor steroids of the androstane series
New A-homo-B, 19-dinor steroids showed strong antiandrogenic activity without affecting the enzyme 5α-reductase or androgen receptor binding.
research Novedades terapéuticas en tricología
Recent advances in hair loss treatments show significant progress.
research Cultured human skin fibroblasts: a model for the study of androgen action
research Spermidine/spermine-N1-acetyltransferase: a key metabolic regulator
SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.