research Differentiation of cultured hair follicle neural crest stem cells into functional melanocytes
Hair follicle stem cells can become melanocytes to help treat skin depigmentation.
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630-660 / 1000+ resultsresearch Functional interrogation of lymphocyte subsets in alopecia areata using single-cell RNA sequencing
CD8+ T cells drive alopecia areata, while regulatory T cells are protective.
research Histology and ultrastructure of canine hair follicle stem cells (cHFSCs)
Canine hair follicle stem cells are located in the isthmus/bulge region of the hair follicle.
research Autofluorescence in the Stem Cell Region of the Hair Follicle Bulge
Autofluorescence in hair follicle stem cells can interfere with studies but may help isolate these cells.
research Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.
A3 antibody helps identify key cells in rat hair follicle development.
research Epidermal cyst containing numerous spherules of keratin
The cyst had unusual keratin spherules and resembled bone marrow.
research Participation of CD34-enriched mouse adipose cells in hair morphogenesis
CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
research CD34 glycoprotein identifies putative stem cells located in the isthmic region of canine hair follicles
CD34 marks potential stem cells in dog hair follicles.
research Localization of Skin Stem Cells of Inner Mongolia Cashmere Goats
Stem cells in cashmere goats are found in hair follicles and have a slow growth rate.
research Melanocyte progenitor cells reside in human subcutaneous adipose tissue
Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.
research Comparative Characterization of Hair Follicle Dermal Stem Cells and Bone Marrow Mesenchymal Stem Cells
Hair follicles can be a good source of stem cells like those from bone marrow.
research Evaluation of immunoreactivity of normal tissues from dogs, using monoclonal antibody B72.3
Monoclonal antibody B72.3 selectively reacts with certain dog tissues, mainly in the gastrointestinal and respiratory tracts.
research “Osler’s phenomenon”: misdiagnosing Cushing’s syndrome
Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.
research Salivary Gland Choristoma (Heterotopic Salivary Gland Tissue) on the Anterior Chest Wall of a Newborn
A newborn girl had a rare case of salivary gland tissue on her chest, which was safely removed.
research Retrospective study of dermatophylosis in sheep in the Sertão of Paraíba
Dermatophylosis sporadically affects adult sheep in Sertão da Paraíba, causing alopecic and crusty skin lesions.
research 020 Sphingosine 1-phosphate receptor signalling promotes hair growth and inhibits perifollicular T-cell expansion and immune privilege collapse ex vivo
research 865 Single-cell protein activity inference analysis of full-thickness skin uncovers novel pathways and a rare Arg1+ macrophage population in AA
Arg1+ macrophages may play a role in Alopecia Areata, offering new treatment targets.
research Decision letter: Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata
ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research Solid basal cell epithelioma (BCE) possibly originates from the outer root sheath of the hair follicle.
Basal cell epithelioma likely starts from the hair follicle's outer root sheath.
research Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations
Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.
research 165 Single-cell RNA sequencing analysis unveils highly active yet diminished CD14+CD16- circulating monocytes, independent of alopecia areata severity
This study investigates the role of circulating monocytes in Alopecia Areata (AA) using single-cell RNA sequencing of peripheral blood mononuclear cells from individuals with mild and severe AA, as well as healthy controls. The analysis reveals a significant depletion of highly active CD14+CD16- monocytes in AA patients, regardless of disease severity, compared to healthy controls. Despite their reduced numbers, these monocytes exhibit heightened metabolic activity and diverse immune responses, including enriched pathways for TLR signaling and interferon-gamma-mediated signaling. The study highlights the paradoxical nature of these monocytes, suggesting their pivotal role in systemic inflammation and potential as therapeutic targets in AA pathogenesis.
research 800 Modulating the butyrophilin-like protein 2 pathway prevents alopecia areata in C3H/HeJ mice
Modulating the BTNL2 pathway can prevent hair loss in mice.
research Table 1_Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata.docx
Alopecia areata involves immune system changes, especially in severe cases, with potential new treatment targets identified.
research Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles
Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.
research Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium
Hair follicle stem cells can become nerve cells using specific treatments.
research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions
Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
research Rekindling the lost hair‐forming world
Non-hairy skin cells might be used to regenerate hair, helping with baldness and skin wounds.
research Abstract 1489: Basal cell carcinomas express functional indoleamine 2,3-dioxygenase (IDO) which may confer immunoprotection
Basal cell carcinomas may use IDO to protect themselves from the immune system.
research CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance
A specific group of skin stem cells was found to help maintain hair follicle cells.