research Label-free concurrent 5-modal microscopy (Co5M) resolves unknown spatio-temporal processes in wound healing
Co5M offers a new way to observe and understand wound healing without labels.
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research Sustained release of inhibitor from bionic scaffolds for wound healing and functional regeneration
Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
research Design of a biofluid-absorbing bioactive sandwich-structured Zn–Si bioceramic composite wound dressing for hair follicle regeneration and skin burn wound healing
Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.
research Novel ECM Patch Combines Poly(vinyl alcohol), Human Fibroblast-Derived Matrix, and Mesenchymal Stem Cells for Advanced Wound Healing
The new ECM patch greatly improves wound healing and tissue regeneration.
research Advancements in transdermal drug delivery using microneedles: technological and material perspective
Microneedle patches offer painless, effective drug delivery and are suitable for all ages.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research Hafnium Oxide Nanostructure-Integrated Silk Fibroin Microneedles Reshape Cutaneous Melanocyte Microenvironment for Vitiligo Therapy
New microneedles may improve vitiligo treatment.
research Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
Smart biomaterials and dressings show promise in treating chronic skin diseases by improving drug delivery and minimizing side effects.
research [Hair follicle cell mixture forms hair follicle-like structures after subcutaneous implantation in nude mice].
Implanted human scalp cells can regenerate hair-like structures in mice.
research Biocompatible chitosan-gelatine-silk hydrogel for the temporary storage of hair follicles during transplantation
research Induction of meibocyte differentiation by three-dimensional, matrigel culture of immortalized human meibomian gland epithelial cells to form acinar organoids
research Author response: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning
Understanding hair follicle interactions can help treat male pattern baldness.
research Janus microneedles enabling orderly vitiligo treatment through spatiotemporal sequential promoting melanogenesis to transfer via PAR2 activation
The study introduces a novel Janus microneedle (Janus MN) designed for vitiligo treatment, which targets immune regulation, melanocyte regeneration, and melanosome transfer. The microneedle features a core-shell bilayer structure, with the shell containing hypericin-assembled nanoparticles and astragalus polysaccharides to improve the microenvironment by reducing oxidative stress and inhibiting immune attacks on melanocytes. The core, containing stabilized trypsin, activates the PAR2 signaling pathway to enhance melanosome transfer, promoting pigmentation. This approach achieves a multidimensional intervention by integrating dual targets within the epidermis and hair follicles, offering a precise, spatiotemporally sequential treatment strategy for vitiligo.
research Can an in vitro hair drug model be developed using dermal papilla cells alone?
Dermal papilla microtissues could be useful for initial hair growth drug testing.
research ANDROGENETIC ALOPECIA: FROM MOLECULAR MECHANISMS TO ADVANCED TOPICAL DELIVERY SYSTEMS WITH EMPHASIS ON POLYMERIC MICELLES
Polymeric micelles offer a promising new way to treat hair loss with fewer side effects.
research Tailoring bioinks of extrusion-based bioprinting for cutaneous wound healing
Improving bioinks can enhance skin healing and regeneration.
research A quantitative technique to analyze and evaluate microstructures of skin hair follicles based on mueller matrix polarimetry
The technique accurately identifies and evaluates hair follicle structures in skin.
research Bioprinting of skin constructs for wound healing
Bioprinting could improve wound healing but needs more development to match real skin.
research A Facile and Biocompatible Hydrogel Based on Oxidized Brachybotrys paridiformis Polysaccharide for Enhanced Wound Healing
The hydrogel significantly speeds up wound healing and improves skin recovery.
research Fabrication of Electrospun Probiotic Functionalized Nanocomposite Scaffolds for Infection Control and Dermal Burn Healing in a Mice Model
Probiotic nanoscaffolds significantly improved burn healing and infection control in mice.
research Recent advances in glycopeptide hydrogels: design, biological functions, and biomedical applications
Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.
research Chitin Derivative‐Based Detachable Microneedles for Effective Treatment of Androgenic Alopecia
Detachable microneedles with chitin derivatives effectively promote hair regrowth in androgenic alopecia without toxicity.
research Silk fibroin nanofibers-GelMA hydrogel composite loaded with embryonic fibroblasts: A strategy for enhanced wound healing
The composite dressing improved wound healing and hair growth in mice.
research Culture of pyramidal neural precursors, neural stem cells, and fibroblasts on various biomaterials
Different materials affect the growth of brain cells and fibroblasts, with matrigel being best for brain cell growth.
research A novel fracture lattice in spiny mouse skin facilitates tissue autotomy and regeneration
Spiny mice have a unique skin structure that helps them heal and regenerate quickly.
research Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment
Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
research Hollow-adjustable polymer microneedles for prolonged hypoglycemic effect on diabetic rats
research Superhydrophobicity for Antifouling Microfluidic Surfaces
Superhydrophobic surfaces can prevent fouling and enable self-cleaning in microfluidic devices.
research Mechanotransduction in Androgenetic Alopecia: An In Silico Repositioning Study of PIEZO1 + MLCK Axis Using Cofolding and Pilosebaceous Single-Cell Atlas Constraints
Potential compounds may inhibit hair loss by targeting a non-androgen pathway.
research Microneedles in cosmetology: A SWOT analysis
Cosmetic microneedles are promising for precise treatments but face challenges like skin damage and regulations.