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Hepatotoxicity Secondary to a Weight Loss Drug, Orlistat: Consideration as a Differential Diagnosis

research Hepatotoxicity Secondary to A Drug to Lose Weight, "Orlistat": to take into Account as a Differential Diagnosis

February 2020 in “Scholars academic journal of pharmacy”

The weight loss drug Orlistat can cause liver damage and should be used with caution, especially in those with liver or kidney issues.

research A Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Anti-Skin-Aging Effect of LactoSporin – The Extracellular Metabolite from Bacillus coagulans (Weizmannia coagulans) MTCC 5856 in Healthy Female Volunteers

16 citations , March 2023 in “Clinical Cosmetic and Investigational Dermatology”

LactoSporin cream reduces wrinkles and improves skin texture safely.

Niosomal Delivery of Pumpkin Seed Oil: Development, Characterization, and Physical Stability

research Niosomal delivery of pumpkin seed oil: development, characterisation, and physical stability

13 citations , February 2019 in “Journal of Microencapsulation”

The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.

Bio-Analytical Method Development and Validation of Finasteride, Tadalafil, and Its Application to Pharmacokinetic Studies in Rat Plasma by Using LC-MS/MS

research BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF FINASTERIDE, TADALAFIL, AND ITS APPLICATION TO PHARMACOKINETIC STUDIES IN RAT PLASMA BY USING LC-MS/MS

September 2024 in “International Journal of Applied Pharmaceutics”

A reliable method was developed to measure Finasteride and Tadalafil in rat blood.

research Pharmacokinetics of Modified Slow-Release Oral Testosterone Over 9 Days in Normal Men With Experimental Hypogonadism

7 citations , May 2012 in “International Journal of Andrology”

The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.

research The Organ-Maintained Human Sebaceous Gland

16 citations , January 1998 in “Dermatology”

Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.

research QOL stable during prophylactic finasteride

September 2012 in “PharmacoEconomics & Outcomes News”

Finasteride doesn't harm quality of life.

Failures of DNA Methylation Clocks and Development of a Noise Barometer for Measuring Epigenetic Pressure of Aging and Disease

research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease

2 citations , September 2023 in “Aging”

Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

research Polyglutamate: Unleashing the Versatility of a Biopolymer for Cosmetic Industry Applications

May 2024 in “Cosmetics”

Polyglutamic acid is a valuable, sustainable ingredient for skincare and haircare products.

research 559 Induction of tissue-specific premature stem cell aging promotes senescence-like phenotypes in remote multiple organs

November 2022 in “Journal of Investigative Dermatology”

Aging in one type of stem cell can cause aging-like changes in various organs.

Developing and Validating an HPLC Method to Quantify Simultaneously Dutasteride and Their Related Molecules (Dutasteride Acid, 2,5 Bis-(Trifluoromethyl)-Aniline and Dutasteride 17 α-Epimer) in Capsules

research DEVELOPING AND VALIDATING AN HPLC METHOD TO QUANTIFY SIMULTANEOUSLY DUTASTERIDE AND THEIR RELATED MOLECULES (DUTASTERIDE ACID, 2,5 BIS- (TRI FLUORO METHYL)-ANILINE AND DUTASTERIDE 17 α-EPIMER) IN CAPSULES

January 2020 in “International Journal of Research in Pharmacy and Chemistry”

A reliable method was created to measure dutasteride and related molecules in capsules.

research Morphologische und histochemische Untersuchungen von Haut. Schleimhäuten und Klauen bei Schweinen mit experimentellem Biotinmangel⁴

8 citations , September 1981 in “Zentralblatt für Veterinärmedizin Reihe A”

Biotin deficiency in pigs causes hair loss, skin issues, and weak claws.

Preparation of Finasteride Capsules-Loaded Drug Nanoparticles: Formulation, Optimization, In Vitro, and Pharmacokinetic Evaluation

research Preparation of finasteride capsules-loaded drug nanoparticles: formulation, optimization, in vitro, and pharmacokinetic evaluation

28 citations , February 2016 in “International Journal of Nanomedicine”

Finasteride capsules with nanoparticles improve drug delivery, solubility, stability, and effectiveness.

research Formulation and design of finasteride coated microneedles

January 2021 in “Zenodo (CERN European Organization for Nuclear Research)”

Finasteride-coated microneedles effectively deliver the drug with minimal scalp damage and high stability.

research Tunable Structured Metal Oxides for Biocatalytic Therapeutics

8 citations , June 2023 in “Advanced functional materials”

Tunable structured metal oxides show promise for various medical treatments due to their versatility and cost-effectiveness.

research [Stem cell niches].

6 citations , September 2007 in “PubMed”

Stem cell niches regulate the number and function of stem cells in the body.

research Characterization of Spanlastic System Loaded Green Tea Extract as Antioxidant for Skin

4 citations , April 2023 in “JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA”

The spanlastic system effectively delivers green tea extract for skincare.

research Cardiometabolic profile of young women with hypoprolactinemia

28 citations , July 2022 in “Endocrine”

Low prolactin in young women may increase heart and metabolism risks.

research Biochemical Insights and Clinical Applications of Ischemia-Modified Albumin in Ischemic Conditions

3 citations , July 2024 in “Journal of Vascular Diseases”

Ischemia-modified albumin can help diagnose ischemic conditions early, but better detection methods are needed.

Self-Adaptive Nanozymes With Enhanced Multi-Enzyme Activities for Sequential Multimodal Therapy of Drug-Resistant Bacteria-Infected Wounds

research Self-adaptive nanozymes with enhanced multi-enzyme activities for sequential multimodal therapy of drug-resistant bacteria-infected wounds

May 2026 in “Nature Communications”

The new treatment effectively heals drug-resistant bacteria-infected wounds.

research Final Report on the Safety Assessment of Human Placental Protein, Hydrolyzed Human Placental Protein, Human Placental Enzymes, Human Placental Lipids, Human Umbilical Extract, Placental Protein, Hydrolyzed Placental Protein, Placental Enzymes, Placental Lipids, and Umbilical Extract

13 citations , April 2002 in “International Journal of Toxicology”

The safety of placental and umbilical extracts in cosmetics is uncertain, requiring more research.

research 17β-Estradiol Enhances Contact Hypersensitivity in a Hair Cycle-Dependent Manner and Retards Thymic Atrophy with Age

5 citations , January 2007 in “Immunopharmacology and Immunotoxicology”

17β-Estradiol boosts allergic reactions and slows thymus aging in mice.

research Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model

22 citations , July 2024 in “Frontiers in Oncology”

This study investigated the tissue-sparing effects of ultra-high dose rate (FLASH) radiation compared to conventional radiation within a Spread-out Bragg Peak (SOBP) in a murine model. Using female CDF1 mice, the study assessed acute and late radiation-induced damage, with doses ranging from 19.9-49.7 Gy for conventional and 30.4-65.9 Gy for FLASH. Results showed that FLASH radiation provided significant normal tissue protection, with a mean protection ratio of 1.40 for acute skin toxicity and 1.18 for fibrotic development. The findings confirm that FLASH radiation within the SOBP maintains its tissue-sparing benefits, offering a 40% reduction in acute skin damage and an 18% reduction in fibrotic development compared to conventional radiation.