research Machine learning driven multi-omics analysis of the genetic mechanisms behind the double-coat fleece formation in Hetian sheep
Key genes IRF2BP2 and EGFR are linked to Hetian sheep's double-coat fleece.
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research Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape
Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.
research Dermatological Changes during Menopause and HRT: What to Expect?
Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.
research Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro
MSC-CM can boost skin cell growth and movement, aiding skin repair.
research Molecular characterization, expression and methylation status analysis of BMP4 gene in skin tissue of Liaoning cashmere goat during hair follicle cycle
BMP4 gene is crucial for hair follicle development in Liaoning cashmere goats.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Stem cell activity shapes the pleiotropic effects of IFN-γ and TGF-β in autoimmune diseases, infections, and cancer, and drives autoimmune flares and remissions
Stem cell activity influences autoimmune disease outcomes by affecting immune responses and tissue regeneration.
research Progress in Gelatin as Biomaterial for Tissue Engineering
Gelatin shows promise for future medical uses due to its safety and versatility, despite some challenges.
research Clinical translational research on stem cell products: prospects and challenges
Stem cell therapy shows promise but needs better safety and quality standards.
research The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases
Exosomes could revolutionize skin disease treatment and healing.
research Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1
Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.
research Genetic and molecular aspects of androgenetic alopecia
Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.
research Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications
Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
research Hair Growth Effect of DN106212 in C57BL/6 Mouse and Its Network Pharmacological Mechanism of Action
DN106212, an extract from a plant, is better at promoting hair growth than other tested substances by affecting hair growth factors and follicle development.
research The G1/S transition in mammalian stem cells in vivo is autonomously regulated by cell size
Cell size controls when stem cells divide.
research Skin aging: mechanisms, evaluation, and rejuvenation
Skin aging can be slowed by targeting cells, hormones, and the microbiome.
research Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling
HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.
research A novel EDA variant that causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family
A new EDA gene variant causes X-linked hypohidrotic ectodermal dysplasia in a Chinese family.
research S100A6: molecular function and biomarker role
S100A6 is important for cell functions and can help diagnose and treat diseases.
research Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche
Melanocyte stem cells in hair follicles are key to understanding and potentially preventing hair graying.
research Micro‐RNA‐31 controls hair cycle‐associated changes in gene expression programs of the skin and hair follicle
miR-31 regulates hair growth by controlling gene expression in hair follicles.
research Empirical evidence of observer bias in randomized clinical trials: updated and expanded analysis of trials with both blinded and non-blinded outcome assessors
Non-blinded assessors tend to overestimate effects in trials by about 29%.
research Deep phenotyping of skin tissue remodeling in patients with systemic sclerosis treated with CD19-CAR T cells
CD19-CAR T cell therapy may help regenerate skin in systemic sclerosis.
research Research progress of gut microbiota and its metabolites in polycystic ovary syndrome
Gut microbiota may significantly influence polycystic ovary syndrome.
research Synergizing biomaterials and cellular molecular pathways: a new frontier in hair follicle generation
Combining biomaterials and cell pathways can improve hair follicle regeneration.
research Platelet-rich plasma—an ‘Elixir’ for treatment of alopecia: personal experience on 117 patients with review of literature
Platelet-rich plasma (PRP) is a simple, cost-effective treatment that promotes hair growth and reduces hair loss, with high patient satisfaction.
research Platelet-rich plasma for the treatment of postoperative anastomotic fistula of the gastrointestinal tract: a case report
Platelet-rich plasma can help heal difficult gastrointestinal fistulas after surgery.
research Keeping up with the neighbours: local synchronisation of cell fate decisions during development
Cells communicate with neighbors to coordinate their development.
research Olfactory epithelium regeneration and homeostasis: cellular and molecular mechanisms and novel methodological advances
The olfactory epithelium can regenerate throughout life, aided by specific cells, genes, and new research methods.
research Human pluripotent stem cell-derived skin organoids enabled pathophysiological model of Mycobacterium tuberculosis infection
Skin organoids can model tuberculosis infection and help test treatments.