31 citations
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August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
26 citations
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July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
22 citations
,
June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
18 citations
,
September 2022 in “Cold Spring Harbor Perspectives in Biology” Controlling immune responses with biomaterials can reduce scarring and improve skin regeneration.
16 citations
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January 1998 in “PubMed” Sun exposure and genetics increase skin cancer risk from precancerous lesions.
14 citations
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January 2019 in “Advances in experimental medicine and biology” Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
9 citations
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February 2014 in “Tissue Engineering and Regenerative Medicine” Conditioned media from human amniotic fluid-derived stem cells helps skin heal and protects against aging from sun exposure.
7 citations
,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
7 citations
,
January 2018 in “Journal of Tissue Viability” An 80-year-old patient grew new hair on a wound, showing that elderly people can still regenerate hair.
4 citations
,
August 2024 in “Dermatological Reviews” Stem cells, PRP, and exosomes help skin heal and rejuvenate, but more research is needed.
4 citations
,
January 2016 in “Methods in molecular biology” HAP stem cells can repair nerves, grow hair follicle nerves, and become heart muscle cells, making them useful for regenerative medicine.
3 citations
,
September 2025 in “Cosmetics” Extracellular vesicles could revolutionize skincare by improving skin repair and anti-aging, but face regulatory and cost challenges.
2 citations
,
May 2020 in “Research Square (Research Square)” Stem cells from diabetic mice can still help heal wounds effectively.
2 citations
,
November 2015 in “Actas Dermo-Sifiliográficas” Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.
1 citations
,
April 2025 in “Frontiers in Medicine” New insights into skin damage from UV exposure suggest potential treatments, including targeting specific RNAs and combining therapies for better outcomes.
June 2025 in “IntechOpen eBooks” Exosomes may improve skin and hair treatments but need more research for safe use.
September 2024 in “Journal of Inflammation Research” Type 1 Diabetes prevents hair growth by causing cell death in hair follicles.
November 2023 in “International Journal of Medical Sciences” New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
September 2022 in “International Journal of Health Sciences (IJHS)” Low zinc levels may contribute to hair loss due to increased oxidative DNA damage.
August 2019 in “Journal of Medical Histology” EMT helps heal tissues but can cause scarring and other issues if prolonged.
March 2019 in “The International Journal of Advanced Smart Convergence” Radish saponin extract may help grow hair in balding mice.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
April 2013 in “Developmental Cell” Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.
December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
January 2012 in “Springer eBooks” The skin has different types of stem cells that can repair and regenerate tissue.
November 2007 in “Science” Keratin-based hydrogels from human hair help nerve repair better than traditional methods.
67 citations
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May 2014 in “International Journal of Molecular Sciences” Using your own skin cells can help repair aging skin and promote hair growth.
35 citations
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September 2009 in “Development” Necl2 affects skin cell behavior and slows wound healing.