146 citations
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January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
55 citations
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April 2015 in “BMC medicine” Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
3 citations
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March 2024 in “Viruses” γδ T cells are essential for wound healing after poxvirus infection.
July 2025 in “Annals of Human Genetics” Genetics play a major role in acne, but environmental factors and epigenetics also contribute.
October 2025 in “Cell Reports” Regulatory T cells help hair growth by using the Cxcr4-Cxcl12 pathway.
286 citations
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June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
212 citations
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January 2017 in “Mediators of Inflammation” Stem cells show promise in speeding up wound healing and tissue regeneration.
88 citations
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July 2020 in “Frontiers in Cell and Developmental Biology” Bioengineered materials improve wound healing by releasing growth factors and cytokines more effectively than traditional methods.
88 citations
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August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
45 citations
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October 2018 in “JCI Insight” Entospletinib effectively prevents eye and skin GVHD in mice.
42 citations
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April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
37 citations
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October 2021 in “Journal of Clinical Investigation” Skin inflammation can worsen intestinal inflammation and colitis.
34 citations
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August 2019 in “Journal of Allergy and Clinical Immunology” mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
33 citations
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February 2024 in “International Journal of Molecular Sciences” Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.
28 citations
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April 2024 in “Immunity” CD80 on skin stem cells helps expand Treg cells to aid wound healing.
25 citations
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November 2020 in “Cell Reports Medicine” Developing human skin has immune cells with memory-like features.
22 citations
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February 2023 in “Heliyon” The hydrogel significantly speeds up wound healing and supports skin cell growth.
19 citations
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January 2023 in “Frontiers in Bioengineering and Biotechnology” MSC-sEVs may effectively treat chronic non-healing wounds.
9 citations
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May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
8 citations
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November 2024 in “EMBO Molecular Medicine” Targeting JAK-STAT1 can reduce inflammation and promote hair growth in conditions linked to EGFR deficiency.
6 citations
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October 2024 in “Frontiers in Bioengineering and Biotechnology” A special hydrogel helps stem cells heal wounds better by boosting growth factors.
4 citations
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August 2025 in “Frontiers in Immunology” Mesenchymal stem cells and their vesicles may effectively treat skin diseases, but more research is needed.
3 citations
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September 2025 in “Cosmetics” Extracellular vesicles could revolutionize skincare by improving skin repair and anti-aging, but face regulatory and cost challenges.
3 citations
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October 2024 in “Experimental Dermatology” Higher CRHR1 levels in AA patients lead to increased inflammation.
2 citations
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November 2025 in “Cells” Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
2 citations
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September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
1 citations
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September 2025 in “Cosmetics” Milk thistle can protect skin from damage and aging.
May 2026 in “Science Advances” Caloric stress and differentiation increase IRES translation, affecting stem cell function and potential therapies.
Reducing nerve growth can help skin regenerate after birth.