research FACILE WATER MEDIATED SYNTHESIS OF FINASTERIDE FORM-I, AN AZAANDROSTANE STEROID
A simple and eco-friendly method was developed to make finasteride Form-I using water.
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research Self-healing and shape-adaptive nanocomposite hydrogels with anti-inflammatory, antioxidant, antibacterial activities and hemostasis for real-time visual regeneration of diabetic wounds
The nanocomposite hydrogels can repair themselves, change shape, reduce inflammation, protect against oxidation, kill bacteria, stop bleeding, and help heal diabetic wounds while allowing for wound monitoring.
research Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration
The hydrogel with bioactive factors improves skin healing and regeneration.
research ‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype
Stromal cells in melanoma promote tumor growth and spread.
research A smart polyhydroxyalkanoate-hyaluronic acid hybrid biphasic delivery platform for enhanced Alzheimer’s symptom management via sustained huperzine A release
The study presents a novel hyaluronic acid-based biphasic delivery platform for Huperzine A (HupA), aimed at improving Alzheimer's disease management. This system encapsulates HupA-loaded polyhydroxyalkanoate nanoparticles within a HA gel matrix, achieving complete drug encapsulation and extending HupA release for over 20 days. In vivo tests on AD mice showed significant therapeutic efficacy, including reduced amyloid-beta deposition, restored cholinergic function, suppressed glial activation, reduced neuroinflammation, enhanced neuronal survival, and preserved synaptic integrity. These effects led to improved spatial memory and reduced anxiety/depression-like behaviors. The study concludes that the HupA@(NP/Gel) system effectively addresses HupA delivery challenges, offering a promising strategy for Alzheimer's intervention.
research Development of Artificial Sebum-containing Leeming and Notman Agar Medium to Enhance the Growth of Malassezia
A new growth medium doubles Malassezia restricta yield by using artificial sebum.
research Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity
Type VII collagen absence helps skin development by allowing tissue remodeling.
research Peritoneal reactions with some of the tubal occlusive agents.
GRF is not safe for tubal occlusion.
research Facilitation of facial prosthesis placement with tattoo markers: A clinical report
Tattoo markers help place ear prostheses easily and improve acceptance.
research Tunable Keratin Hydrogels for Controlled Erosion and Growth Factor Delivery
Keratin hydrogels can be customized for better tissue healing.
research A Trilayer Dressing with Self-Pumping and pH Monitoring Properties for Promoting Abdominal Wall Defect Repair
The new wound dressing helps heal abdominal wall defects faster by improving the wound environment.
research Advancements and Applications of Injectable Hydrogel Composites in Biomedical Research and Therapy
Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.
research Symbiotic in vitro seed propagation of Dendrobium: fungal and bacterial partners and their influence on plant growth and development
Certain fungi and bacteria help orchid seeds germinate and plants grow better.
research MORPHOLOGICAL CHARACTERISTICS OF ACELLULAR DERMAL MATRIX MANUFACTURING
The method effectively creates acellular dermal matrix from pig skin while preserving structure.
research Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation
MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
research Bead-jet printing enabled sparse mesenchymal stem cell patterning augments skeletal muscle and hair follicle regeneration
Bead-jet printing of stem cells improves muscle and hair regeneration.
research Advances in nitric oxide-releasing hydrogels for biomedical applications
research An Innovative Approach to Platelet-Rich Plasma Application in Military Medicine; a Review Article
Platelet-rich plasma (PRP) shows promise in military medicine but its effectiveness varies.
research Harnessing Milk-derived Extracellular Vesicles for Oral Drug Delivery and Therapeutic Application
research Malignant Melanoma and Its Stromal Nonimmune Microecosystem
The surrounding tissue plays a crucial role in the growth and spread of skin cancer.
research Composite Hydrogel Dressing with Drug-Release Capability and Enhanced Mechanical Performance
The hydrogel dressing improves wound healing, offers long-lasting antibacterial effects, and enhances patient comfort.
research Elaboration of hollow mesoporous organosilica nanospheres of various sizes
Hollow mesoporous organosilica nanoparticles are promising for biomedical use.
research Clinically relevant skull models and optical measurement method to evaluate programmable hydrocephalus valve tool kit usability
Three skull models were found most useful for testing hydrocephalus valve programming.
research Development of modified montmorillonite-bacterial cellulose nanocomposites as a novel substitute for burn skin and tissue regeneration
New nanocomposites with copper show promise for healing burn wounds and regenerating skin.
research Highway Deconstruction
The document concludes that human astrocytes aid stroke recovery, research confidence affects student career aspirations, collagen affects cancer spread, a microRNA suppresses brain cancer growth, calmodulin regulates water channels, and small magnesium pieces deform differently.
research Evaluation of the Effectiveness of Mesenchymal Stem Cells of the Placenta and Their Conditioned Medium in Local Radiation Injuries
Placental mesenchymal stem cells and their conditioned medium significantly improve healing in local radiation injuries.
research A self-healing hydrogel wound dressing based on oxidized Bletilla striata polysaccharide and cationic gelatin for skin trauma treatment
The hydrogel made from plant polysaccharide and gelatin helps wounds heal faster by absorbing fluids and maintaining a moist healing environment.
research Magneto-responsive biocomposites in wound healing: from characteristics to functions
Magneto-responsive biocomposites help heal wounds faster and better.
research 未利用資源の乳酸菌発酵による高付加価値化と化粧品原料への応用
Lactic acid bacteria fermentation can turn waste into valuable skincare ingredients.
research Hydrogel-Forming Microneedles for Transdermal Drug Delivery
Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.