Search

for
Search:

Did you mean Epithelialization?

GlossaryEpithelialization

process of new skin cells covering a wound

Epithelialization is the process by which new epithelial cells form and migrate to cover a wound or damaged tissue, creating a protective barrier. This is a crucial step in wound healing, as it helps to restore the integrity of the skin or mucous membranes, preventing infection and further injury.

Related Terms

Sort by

Research

30 / 1000+ results

research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis

47 citations , September 2012 in “Human molecular genetics online/Human molecular genetics”

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

research Autonomous, Moisture‐Driven Flexible Electrogenerative Dressing for Enhanced Wound Healing

23 citations , February 2025 in “Advanced Materials”

The dressing speeds up wound healing by 41% using moisture-generated electricity and antibacterial properties.

research Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model

8 citations , January 2024 in “Journal of Materials Chemistry B”

ADM hydrogels help heal radiation skin injuries.

research The expanding significance of keratin intermediate filaments in normal and diseased epithelia

186 citations , December 2012 in “Current opinion in cell biology”

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

research Keratins in health and cancer: more than mere epithelial cell markers

438 citations , October 2010 in “Oncogene”

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

research eLife assessment: Decoding the complexity of delayed wound healing following Enterococcus faecalis infection

May 2024

Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.

research ILK modulates epithelial polarity and matrix formation in hair follicles

22 citations , December 2013 in “Molecular biology of the cell”

ILK is essential for proper hair follicle development and structure.

Bioactive Anti-Inflammatory Antibacterial Hemostatic Citrate-Based Dressing With Macrophage Polarization Regulation for Accelerating Wound Healing and Hair Follicle Neogenesis

research Bioactive antiinflammatory antibacterial hemostatic citrate-based dressing with macrophage polarization regulation for accelerating wound healing and hair follicle neogenesis

61 citations , September 2020 in “Bioactive Materials”

A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.

research Choreographing Immunity in the Skin Epithelial Barrier

57 citations , March 2019 in “Immunity”

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity

24 citations , July 2018 in “Stem cells”

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

research Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages

14 citations , February 2014 in “Experimental Cell Research”

The conclusion is that teeth, hair, and claws have similar stem cell niches, which are important for growth and repair, and more research is needed on their regulation and potential markers.

research Scaffolds for epithelial and hair follicle regeneration

1 citations , January 2019 in “Elsevier eBooks”

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

Morphogenesis and Maintenance of the 3D Thymic Medulla and Prevention of Nude Skin Phenotype Require FoxN1 in Pre- and Post-Natal K14 Epithelium

research Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium

21 citations , November 2010 in “Journal of molecular medicine”

FoxN1 gene is essential for proper thymus structure and preventing hair loss.

research In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation

1 citations , June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.

research 1378 Identification of two distinct stem cell clusters, Lrig1-derived and Wnt/CD44-dependent, in corneal epithelium

April 2018 in “Journal of Investigative Dermatology”

The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.

research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis

102 citations , August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Cepharanthine attenuates pulmonary fibrosis via modulating macrophage M2 polarization

6 citations , September 2024 in “BMC Pulmonary Medicine”

Cepharanthine may help treat lung fibrosis by affecting certain immune cells.

Functional Characterization of OR51B5 and OR1G1 in Human Lung Epithelial Cells as Potential Drug Targets for Non-Type 2 Lung Diseases

research Functional characterization of OR51B5 and OR1G1 in human lung epithelial cells as potential drug targets for non-type 2 lung diseases

4 citations , November 2024 in “Cell Biology and Toxicology”

Blocking certain receptors in the lungs might help treat a specific type of asthma.

research Cell Polarization Defects in Early Heart Development

9 citations , July 2007 in “Circulation Research”

Defects in certain proteins cause major heart abnormalities during early development.

research Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus

184 citations , September 2006 in “PLoS Genetics”

The Apc gene is crucial for normal skin and thymus development.

research CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation

3 citations , June 2025 in “Journal of Cellular and Molecular Medicine”

CuATSM speeds up wound healing and reduces scarring.

research Types I and II Keratin Intermediate Filaments

211 citations , April 2018 in “Cold Spring Harbor Perspectives in Biology”

Keratins are crucial for cell structure, growth, and disease risk.

research Early inductive events in ectodermal appendage morphogenesis

160 citations , January 2014 in “Seminars in cell & developmental biology”

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

research Immune-Epithelial Cross Talk in Regeneration and Repair

52 citations , January 2023 in “Annual Review of Immunology”

Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

research Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire

40 citations , March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

research Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns

33 citations , June 2017 in “Developmental Biology”

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche

6 citations , May 2013 in “PloS one”

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

Epigenetic Orchestration of RNA m6A Methylation in Wound Healing and Post-Wound Events

research Epigenetic orchestration of RNA m⁶A methylation in wound healing and post-wound events

3 citations , July 2025 in “International Journal of Biological Sciences”

m⁶A methylation is crucial for proper wound healing and tissue repair.

research Innervated Biomaterials for Improved Cutaneous Wound Healing: A Review of Recent Advancements and Future Prospects

2 citations , June 2025 in “International Journal of Nanomedicine”

New biomaterials can improve wound healing by promoting nerve and tissue regeneration.

Hair-Follicle Associated Pluripotent Cell-Sheet Implantation Enhanced Wound Healing in Diabetic db/db Mice

research Hair-follicle associated pluripotent (HAP)-cell-sheet implantation enhanced wound healing in diabetic db/db mice

1 citations , June 2024 in “PLoS ONE”

HAP-cell-sheets improved wound healing in diabetic mice.