July 2026 in “Theranostics” The study presents a ferritin-based nanocage (LR@Fn) as a novel co-delivery system for protecting hair cells and attenuating hearing loss. This system effectively delivers small molecules RG108 and LLY283 directly to the inner ear, overcoming challenges like poor cellular uptake and off-target toxicity. In models of neonatal cisplatin and adult noise-induced hearing loss, LR@Fn demonstrated superior protection of hair cells, reduced synaptic damage, and decreased apoptosis compared to dexamethasone. The treatment also activated the Wnt/β-catenin pathway, contributing to its protective effects. LR@Fn shows promise as a biocompatible platform for targeted inner-ear therapy across various forms of hearing loss.
85 citations
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July 2025 in “Nature Communications” Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.
1 citations
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April 2026 in “Cancer Nanotechnology” Nanozymes could improve cancer diagnosis and treatment by mimicking enzymes and enhancing delivery to tumors.
51 citations
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January 2024 in “Nanoscale” Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
January 2024 in “Regenerative Biomaterials” Metal organic frameworks-based scaffolds show promise for tissue repair due to their unique properties.
24 citations
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November 2023 in “Regenerative Biomaterials” Metal ions can help treat heart diseases by protecting cells and repairing tissues.
5 citations
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December 2023 in “Materials” Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
2 citations
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September 2024 in “Journal of intelligent medicine.” Rational design strategies are crucial for developing effective nanozymes for anti-inflammatory uses.
46 citations
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October 2025 in “Journal of Nanobiotechnology” Plant-derived nanovesicles show promise for treating skin issues like hair loss and aging.
83 citations
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April 1992 in “Clinical Endocrinology” Having enough iron improves the effectiveness of a specific hair loss treatment in women.
21 citations
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January 2009 in “Indian journal of dermatology, venereology, and leprology” Vitamin B12, folate, ferritin, and iron levels are not linked to alopecia areata.
16 citations
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January 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Low levels of vitamin B12 and ferritin are linked to early hair graying.
10 citations
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January 2012 in “International Journal of Trichology” The study found no link between anxiety, vitamin B12, folate, TSH, ferritin, zinc levels, and trichodynia in telogen alopecia patients.
7 citations
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January 2016 in “Hair therapy & transplantation” People with early graying hair often have lower levels of iron, ferritin, and calcium.
7 citations
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October 2011 in “Faṣlnāmah-i bīmārīhā-yi pūst” Iron and ferritin levels don't affect alopecia areata.
6 citations
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January 2020 in “Postepy Dermatologii I Alergologii” Check and treat low iron and vitamin D levels in people with hair loss.
6 citations
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August 2023 in “Journal of Investigative Dermatology” Skin plays a key role in managing iron levels, and inflammation can affect systemic iron, potentially causing anemia.
5 citations
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August 2020 in “Advances in Hematology” Automatically measuring ferritin can help identify iron deficiency in women with hair loss.
4 citations
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June 2018 in “PLOS ONE” Iron levels are linked to insulin resistance in men and postmenopausal women, but not in premenopausal women.
3 citations
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May 2022 in “Indian Journal of Dermatology” Low ferritin and high Anti TPO levels are linked to early hair greying.
2 citations
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July 2022 in “Dermatology practical & conceptual” Iron deficiency anemia may contribute to hair loss in women with Telogen effluvium.
2 citations
,
September 2012 in “Turk Dermatoloji Dergisi” Low levels of ferritin and vitamin B12 are common in women with telogen effluvium, but the link between nutrient deficiencies and the condition is not clear.
1 citations
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August 2023 in “Cutis” Low ferritin levels can indicate iron deficiency as a cause of hair loss.
1 citations
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July 2021 in “Fayoum University Medical Journal” Men with hair loss have lower vitamin D levels.
1 citations
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April 2021 in “International Journal of Research in Dermatology” Low iron and vitamin B12 levels are common in women with chronic hair loss, while low vitamin D is less common.
1 citations
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January 2021 in “International journal of pharmaceutical research” Low levels of ferritin, TSH, and certain vitamins are linked to hair loss in women of different ages.
1 citations
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October 2020 in “IP Indian journal of clinical and experimental dermatology” Low serum ferritin levels are significantly linked to diffuse hair loss.
1 citations
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January 2018 in “Annals of medical research” No link found between blood groups, Rhesus factor, and ferritin levels in women with hair loss.
November 2025 in “Khalij-Libya Journal of Dental and Medical Research” Hair loss is linked to low levels of zinc, vitamin D, and ferritin.
September 2025 in “Romanian Journal of Medical Practice” Iron deficiency is linked to female pattern hair loss.