research Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride
Dutasteride does not impair mental function in elderly men with enlarged prostate.
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research Does prolactin play a role in skin biology and pathology?
Prolactin may be important for skin growth and immune function.
research Advances in male hormone substitution therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Basic mechanisms of SARS-CoV-2 infection. What endocrine systems could be implicated?
SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.
research Calcineurin-based immunosuppression in renal transplantation : focus on efficacy, the role of steroids, and the cardiovascular risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
research The impact of exogenous vitamin D on thyroid autoimmunity in euthyroid men with autoimmune thyroiditis and early-onset androgenic alopecia
Vitamin D may help reduce antibody levels in men with autoimmune thyroiditis and early-onset androgenic alopecia, but has no significant impact on thyroid function.
research Finasteride
Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
research Resveratrol Ameliorates the Seminiferous Tubules Damages Induced by Finasteride in Adult Male Rats
Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.
research The Rotterdam Study: 2016 objectives and design update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research Characteristic Localization of Neuronatin in Rat Testis, Hair Follicle, Tongue, and Pancreas
Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
research Dose–Response Effects of Oral Melatonin on Reproductive Parameters in Intact Male Pomeranian Dogs With Alopecia X: A Controlled Study
Melatonin improved reproductive function in male Pomeranian dogs with Alopecia X, but more research is needed.
research Male Sex Hormones in Andrology Today
Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
research “Sebocytes’ makeup” - Novel mechanisms and concepts in the physiology of the human sebaceous glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study
Five preservatives may disrupt hormone function and need more health and environmental risk assessment.
research Enhanced Sensitivity to Ethanol-Induced Inhibition of LTP in CA1 Pyramidal Neurons of Socially Isolated C57BL/6J Mice: Role of Neurosteroids
Social isolation makes mice more sensitive to alcohol's effects on brain function.
research Peroxisome Proliferator–Activated Receptor-γ−Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium
PPAR-γ signaling improves mitochondrial function in hair follicles, potentially affecting hair growth and aging.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Obesity and Wound Healing: Focus on Mesenchymal Stem Cells
Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.
research Anatomy and Physiology of the Skin
The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
research Efficacy and safety of glucocorticoids in the treatment of progressive muscular dystrophy in children: a systematic review and meta-analysis
Glucocorticoids for progressive muscular dystrophy in children don't improve muscle strength or function but do increase certain side effects.
research Inconsistent effects of surgical and chemical castration on arterial baroreceptor dysfunction and cardiac and brainstem inflammation in endotoxic rats
Surgical and chemical castration have varied effects on heart and brain inflammation and artery function in sick rats.
research Adverse effects of common medications on male fertility
Some common medications can harm male fertility, but many effects can be reversed.
research Oestrogen functions in skin and skin appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Transcranial photobiomodulation for brain diseases: review of animal and human studies including mechanisms and emerging trends
Light therapy on the brain shows promise for treating brain diseases and improving brain function.
research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity
Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
research Emerging medication for the treatment of male hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research Stem cells and the circadian clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?
The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.