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research Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice

2 citations , March 2022 in “Laboratory Animal Research”

A mild botulinum toxin injection improved sperm production and movement in aging mice.

research Alopecia in Belgian Blue crossbred calves: a case series

November 2019 in “BMC veterinary research”

The hair loss in Belgian Blue crossbred calves was caused by a diet issue, not by disease or infection.

research Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction

87 citations , July 2009 in “Journal of Cell Science”

Deleting the CDSN gene causes severe skin and hair problems, leading to death.

research Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production

40 citations , July 2019 in “Journal of Investigative Dermatology”

Lack of a key enzyme causes severe skin issues and death in mice.

research Establishment and characterization of a radiation‐induced dermatitis rat model

16 citations , February 2019 in “Journal of Cellular and Molecular Medicine”

Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.

research Optical Behavior of Human Skin Substitutes: Absorbance in the 200–400 nm UV Range

15 citations , July 2022 in “Biomedicines”

UGRSKIN absorbs UV like native skin after 21-28 days, making it potentially suitable for clinical use.

research Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages

6 citations , December 2022 in “Cell reports”

Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.

research Allergic Dermatitis in Pêga Breed Donkeys (Equus asinus) Caused by Culicoides Bites in the Amazon Biome, Pará, Brazil

4 citations , April 2024 in “Animals”

Copaiba oil and multivitamin emulsion can effectively treat allergic dermatitis in donkeys caused by Culicoides bites.

research SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling

4 citations , March 2024 in “Journal of Investigative Dermatology”

SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

research Evaluation of Biological Activity Exerted by an Aza-bicyclocarboxylic acid Derivative using Anischemia-Reperfusion Injury Model

3 citations , December 2018 in “Biomedical and pharmacology journal/Biomedical & pharmacology journal”

Compound 3 protects the heart from damage by activating A1-adenosine receptors.

research The mammary hair of Monodelphis domestica and homology of the mammary pilosebacous unit

1 citations , August 2024 in “Journal of Morphology”

Mammary glands evolved from hair organs in Monodelphis domestica.

research Hair follicle transplantation promotes skin ulcer healing in a mouse model of experimental diabetes

August 2025 in “Scientific Reports”

Hair follicle transplantation speeds up wound healing in diabetic mice.

Microinjury-Induced Tumor Necrosis Factor-Alpha Surge Stimulates Hair Regeneration in Mice

research Microinjury-Induced Tumor Necrosis Factor-α Surge Stimulates Hair Regeneration in Mice

January 2023 in “Skin Pharmacology and Physiology”

Minor injuries to hair follicles can stimulate hair growth in mice by increasing a specific protein.

research Delayed hair cycle in mnd2 mutant mice lacking HtrA2 serine protease activity

December 2022 in “Biochemical and Biophysical Research Communications”

HtrA2 activity is crucial for normal hair growth by regulating fat cell development.

research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases

97 citations , May 2019 in “Frontiers in Cell and Developmental Biology”

Abnormal ECM and immune cell interactions can cause skin diseases.

research The role of the microbiome in scalp hair follicle biology and disease

73 citations , April 2019 in “Experimental Dermatology”

The scalp's microorganisms significantly affect hair health and disease.

research Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity

70 citations , August 2006 in “Cancer Research”

AP-1 controls tumor cell type by affecting key signaling pathways.

research Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation

54 citations , December 2011 in “American Journal Of Pathology”

A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.

research Morphea: progress to date and the road ahead

50 citations , March 2021 in “Annals of Translational Medicine”

More research is needed to understand and treat morphea effectively.

Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration After Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus

research Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration after Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus

49 citations , March 2014 in “Journal of Investigative Dermatology”

Using the drugs AMD3100 and Tacrolimus together greatly improves skin healing and hair growth after a deep skin cut by increasing stem cells in the wound.

research Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

46 citations , September 2023 in “Cell Reports”

Sebaceous glands can regenerate after injury using stem cells from hair follicles.

research Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings

37 citations , August 2024 in “Current Issues in Molecular Biology”

Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.

research Parsing patterns: Emerging roles of tissue self-organization in health and disease

22 citations , June 2024 in “Cell”

Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.

research Effect ofCinnamomum osmophloeumKanehira Leaf Aqueous Extract on Dermal Papilla Cell Proliferation and Hair Growth

20 citations , February 2018 in “Cell transplantation”

Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.

research A randomized, controlled clinical trial of autologous stromal vascular fraction cells transplantation to promote mechanical stretch-induced skin regeneration

19 citations , April 2021 in “Stem Cell Research & Therapy”

SVF cell transplantation improves skin regeneration safely.

research SIRT1-modified human umbilical cord mesenchymal stem cells ameliorate experimental peritoneal fibrosis by inhibiting the TGF-β/Smad3 pathway

17 citations , August 2020 in “Stem Cell Research & Therapy”

The study investigated the therapeutic potential of SIRT1-modified human umbilical cord mesenchymal stem cells (hUCMSCs) for treating peritoneal fibrosis, a complication of long-term peritoneal dialysis. By overexpressing SIRT1, these modified cells showed a stronger anti-fibrosis effect compared to regular hUCMSCs by significantly inhibiting fibrotic gene expression, suppressing the epithelial-mesenchymal transition (EMT) process, increasing ultrafiltration volume, and restoring the balance of bioincompatible factors in dialysis solutions. The mechanism involved reducing peritoneal inflammation and inhibiting the TGF-β/Smad3 pathway. The study involved 8 rats per group and demonstrated that SIRT1-modified hUCMSCs could be a promising therapeutic strategy for peritoneal dialysis-induced peritoneal damage and fibrosis.

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