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A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.

Secondary aesthetic surgeries for gender reassignment are generally satisfying and advance overall aesthetic surgery techniques, but psychological support is important.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.

A rare ovarian tumor caused a postmenopausal woman to develop male-like features, which improved after surgery.

A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Topical finasteride can cause breast enlargement and tenderness in men.

Gender-affirming hormone therapy and surgery affect gut bacteria differently.

A postmenopausal woman's increased male hormone levels were successfully treated with surgery.

Facial hair is crucial for transgender men's gender identity and transition.

Proper management of the dilation program is crucial after male-to-female reassignment surgery.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

A 22-year-old woman with a rare genetic condition was successfully treated to develop normal female characteristics and regular menstruation.

Thorough evaluation is crucial for postmenopausal women with virilization to detect rare ovarian tumors.

Understanding gender differences and individual patient characteristics is essential for optimal cosmetic surgery outcomes.

A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.

A man developed hair loss from testosterone treatment but improved with additional medication.

The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

Beard hair can be successfully transplanted to the moustache area for facial hair restoration with high patient satisfaction.

Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.