10 citations
,
January 2017 in “Dermatology Online Journal” Metformin helps treat moderate-to-severe acne when used with other treatments.
2 citations
,
July 2019 in “Digital Showcase Research, Scholarship, & Creative Works (University of Lynchburg)” No proven link between isotretinoin and depression.
18 citations
,
August 2011 in “Clinical Drug Investigation” Low-dose isotretinoin combined with pulsed azithromycin cleared acne in most patients, with mild side effects.
November 2025 in “Journal of Multidisciplinary Healthcare” Combining fire needle therapy with doxycycline improves severe acne more than doxycycline alone.
December 2023 in “Journal of Cosmetic Dermatology” Baricitinib effectively and safely improves hair growth in patients with severe alopecia areata.
October 2025 in “Figshare” Deuruxolitinib improves hair regrowth in alopecia areata but needs more safety research.
October 2025 in “Figshare” Deuruxolitinib effectively treats alopecia areata but may cause manageable side effects.
A new acne cream effectively reduced acne in trials and awaits FDA approval.
10 citations
,
July 2019 in “Indian Journal of Dermatology” Weekly azathioprine pulse is a better alternative to corticosteroids for treating alopecia areata due to fewer side effects.
2 citations
,
October 2025 in “Frontiers in Medicine” Deuruxolitinib effectively improves hair regrowth in alopecia areata but requires monitoring for side effects.
20 citations
,
April 2020 in “Journal of advanced Biomedical and Pharmaceutical Sciences” Niosomal methylene blue gel effectively improves moderate to severe acne.
4 citations
,
April 2016 in “Journal of Dermatology Research and Therapy” Anti-androgens are safe and effective for treating moderate to severe adult female acne.
July 2025 in “Canadian Family Physician” Use topical treatments for mild acne and oral treatments for moderate to severe acne, avoiding antibiotic monotherapy.
31 citations
,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
21 citations
,
April 2011 in “Clinical Cosmetic and Investigational Dermatology” Acne treatment varies by severity, using topical treatments for mild cases, combination therapies for moderate cases, and oral isotretinoin for severe cases, with hormonal treatments for some women.
December 2025 in “International Journal of Research in Dermatology” Isotretinoin effectively treats severe acne but has serious side effects and requires careful monitoring.
December 2010 in “Zanco Journal of Medical Sciences” Acne is more common and severe in females, often with pre-menstrual flare-ups and associated with seborrhea.
October 2024 in “INNOVATION RESEARCH JOURNAL” More severe acne leads to a lower quality of life for teenagers.
December 2022 in “Cureus” Adult women with acne in Iraq often have more severe symptoms and hormone-related issues than younger girls with acne.
Use mild topical steroids to avoid side effects, especially in children.
October 2024 in “International Journal of Research in Dermatology” Tofacitinib is a promising and safe treatment for moderate to severe alopecia areata.
January 2019 in “OpenBU/Boston University Institutional Repository (Boston University)” Women with PCOS often show signs of excess androgens like hirsutism, acne, and alopecia, with variations across ethnic groups.
29 citations
,
January 2007 in “Dermatologic Clinics” Photodynamic Therapy is an effective treatment for mild to severe acne.
6 citations
,
January 1997 in “Pediatric dermatology” The case suggests a possible link between severe acne and certain bone deformities.
January 2023 in “Dermatologic Therapy” A new hand-held light therapy device was found to be safe and effective for treating mild-to-moderate acne.
16 citations
,
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” Birth control pills can help reduce mild to moderate acne in women.
1 citations
,
April 2019 in “Journal of Investigative Dermatology” VB1953 gel significantly reduced acne and resistant bacteria in patients who didn't respond to clindamycin.
September 2023 in “PubMed” Baricitinib is a relatively safe and effective treatment for severe alopecia areata.
May 2025 in “Lasers in Surgery and Medicine” Nonablative monopolar radiofrequency is a safe and effective long-term treatment for acne.
December 2024 in “European Journal of Dermatology” Transgender acne treatment requires a tailored approach with ongoing topical treatments and ceramide-rich moisturizers.