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The April 2016 JEADV issue covered various dermatology topics, including psoriasis, psoriatic arthritis, mTOR inhibitors, autoimmune diseases, photodynamic therapy, viral DNA in skin diseases, chronic hand eczema, and female hair loss.

Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.

Epigenetic and metabolic changes affect stem cell function and aging in skin.

In 2023, there were major advancements in skin and venereal disease treatments.

Blocking mTORC1 reduces skin tumor growth in mice.

Blocking mTORC1 may help prevent skin cancer by stopping the growth of certain skin stem cells.

mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.

Mitochondrial genes help predict breast cancer outcomes and spread.

Radiotherapy affects mitochondrial-related genes in metastatic breast cancer cells.

Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.

ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

MK-5108 is safe and shows potential against tumors, especially alone.

Matriptase imbalance contributes to cancer development and spread.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Mitf plays a key role in melanoma progression and is linked to disease stage.

High energy boosts root hair growth in plants, while low energy stops it.

Stem cells can be primed to respond faster to injury through mTORC1 signaling, enhancing muscle regeneration.

FER and TOR signaling help root hair growth in low temperature and low nitrate conditions.

Minoxidil increases cell layer permeability by reducing tight junction proteins and raising ROS levels.

MOF controls skin development by regulating genes for mitochondria and cilia.

Inhibiting the PI3K/Akt pathway may help prevent radiation-induced liver injury.

TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.

Mitochondrial features can predict colorectal cancer outcomes and improve immunotherapy.

ROR2 is crucial for hair follicle stem cell maintenance and self-renewal.

A woman developed thick gums from everolimus treatment after a kidney transplant.