research Signaling from keratins
Keratin 17 is crucial for cell growth in wound healing by aiding protein synthesis.
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30-60 / 1000+ resultsresearch Androgen receptor signaling as a new target for intervention in acute myeloid leukemia
Targeting androgen receptor signaling may improve acute myeloid leukemia treatment.
research 878 Influence of bovine milk oligosaccharides on sebocyte lipid content and inflammatory mediators
Cow milk sugars increase fat production and inflammation in skin oil cells.
research 202 MicroRNAs in the pathogenesis of male pattern baldness
Different levels of microRNAs in different parts of the scalp can cause male pattern baldness.
research The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis
mTOR inhibitors may help treat lung fibrosis.
research A preview of selected articles
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
research Isoquercitrin promotes hair growth through induction of autophagy and angiogenesis by targeting AMPK and IGF-1R
Isoquercitrin helps hair grow by activating certain cell processes.
research Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives
Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.
research A symphony of signals: the intricate role of lncRNAs in dermatological disorders
lncRNAs are important for understanding and treating skin diseases.
research Frontal fibrosing alopecia: A review of disease pathogenesis
The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
research Exploring the mechanism of Notopterygii rhizoma et radix in the treatment of psoriasis using a network Pharmacology approach and experimental validation
Notopterygii rhizoma et radix (Qiang Huo) can effectively treat psoriasis by reducing skin symptoms and inflammation.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research LHX2: a transcription factor in development, homeostasis, repair, and disease
LHX2 is crucial for development, tissue repair, and preventing diseases.
research Molecular Mechanisms of Vitexin: An Update on Its Anti-Cancer Functions
Vitexin shows promise as a cancer treatment by affecting key cellular processes and pathways.
research Morphological and functional analysis on M3R mediated sweating in TSC1 k/o mouse
Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.
research Canonical and emerging regulatory mechanisms of tissue remodeling: shared principles across organs and therapeutic opportunities
Understanding tissue remodeling can help create precise treatments for various organ issues.
research Targeting the Warburg Effect in Anaplastic Thyroid Carcinoma: Metabolic Vulnerabilities and Therapeutic Opportunities
Targeting the Warburg effect in anaplastic thyroid carcinoma may reduce tumor growth and improve treatment.
research Anticancer Effects of Cepharanthine: an Updated Minireview
Cepharanthine shows promise as a natural anticancer treatment.
research The role of glucose metabolism in wound healing: an overview
Glucose metabolism is crucial for wound healing but can delay healing in chronic wounds due to increased stress and inflammation.
research The relationship between keratin 18 and epithelial-derived tumors: as a diagnostic marker, prognostic marker, and its role in tumorigenesis
Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.
research Keratins 6, 16, and 17 in Health and Disease: A Summary of Recent Findings
Keratins 6, 16, and 17 increase in damaged or diseased skin and may help diagnose skin issues.
research Androgen receptor: A promising therapeutic target in breast cancer
The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
research Molecular landscape of lung cancer: insights into therapeutic targets and clinical outcomes
New treatments targeting genetic mutations in lung cancer are needed for better outcomes.
research Transplantation of bone mesenchymal stem cells effectively promotes intestine regeneration to eliminate endotoxemia and reduce mortality in the animal model of acute liver failure
Bone marrow stem cells help heal intestines and reduce death in liver failure.
research mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration
mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
research Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways
Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.
research Cutaneous gain-of-function mutation of LRIG3 leads to alopecia by upregulation of ERBB, PI3K/AKT, NOTCH1 signaling pathways
Overexpression of LRIG3 in skin causes hair loss.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
research An analysis of gene expression data involving examination of signaling pathways activation reveals new insights into the mechanism of action of minoxidil topical foam in men with androgenetic alopecia
Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.
research Vitamin B6 promotes the activation of primordial follicles through the PI3K/Akt signaling pathway
Vitamin B6 may help activate dormant follicles.