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IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.

Wharton's jelly stem cells show diverse traits and functions.

T cells and inflammation are crucial in atherosclerosis, with anti-inflammatory treatments showing promise.

Large-scale fibronectin nanofibers help heal wounds and repair tissue in a skin model of a mouse.

Electrospun nanofiber membranes are promising for non-invasive medical uses like tissue repair and health monitoring.

Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Controlling cellular changes can enable safe rejuvenation without cancer risk.

Pomegranate has health benefits and new methods are improving its use in supplements.

Non-coding RNAs could help detect and treat radiation damage.

Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.

Tryptanthrin effectively suppresses non-melanoma skin cancer and is safe for normal skin.

Hydrogel microneedles offer a painless, effective way to treat skin disorders.

Single-cell encapsulation shows promise for medical use but faces production challenges.

Hydrogels can enhance stem cell activity, but more research is needed to optimize their use.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Nociplastic pain is a complex, heritable trait with genetic links to chronic and neuropathic pain.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.

TRPV channels are important in osteoarthritis and could be key to new treatments.

Extracellular vesicles can help repair and regenerate tissues with less risk of rejection.

Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.

Exosomes from umbilical cord stem cells help heal complex perianal fistulas in rats.

Cell membrane-coated nanoparticles could improve gene therapy by enhancing delivery and targeting of nucleic acids.

Plant-derived exosomes can help deliver drugs and enable communication between different organisms.

In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.

Photobiomodulation therapy can reduce pain and inflammation and help heal tissues, but more research is needed to improve its effectiveness and safety.

High DHA levels delay wound healing and worsen skin repair quality.

Natural products may help treat Non-Small Cell Lung Cancer by causing cancer cell death through ferroptosis.