research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
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research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
research p75 Neurotrophin Receptor Antagonist Retards Apoptosis-driven Hair Follicle Involution (Catagen)
Blocking a specific receptor slows down hair loss in mice.
research Sex steroid levels in corresponding cerebrospinal fluid and serum samples quantified by mass spectrometry in men
DHEA is the main sex steroid in cerebrospinal fluid, and testosterone in the fluid comes from the blood.
research Finding Parallels
Human stem cells can aid stroke recovery, research experiences boost students' career aspirations, minoxidil may reduce cancer spread, a molecule can slow tumor growth, a protein affects water flow in cells, magnesium behaves differently at tiny scales, and a new method detects slow-moving objects.
research Pericyte Plasticity in the Brain
research Cell-derived exosome therapy for diabetic peripheral neuropathy: a preclinical animal studies systematic review and meta-analysis
Exosome therapy may help treat diabetic nerve damage, but more research is needed.
research Non-invasive Management of Head and Neck Neuralgia: A Literature Review
Customizing non-invasive treatments for head and neck neuralgia improves patient outcomes.
research Endocrine Aspects of Female Sexual Dysfunction
Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
research In Vitro differentiation of hair-follicle bulge stem cells into synaptophysin-expressing neurons: a potential new approach for neuro-regeneration
Hair follicle stem cells can be turned into neuron-like cells, offering a new way for brain repair.
research Steroid Hormones of Reproduction and Sexual Development
Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.
research Cutaneous Corticosteroid Injection and Amaurosis
Smaller, diluted corticosteroid injections reduce the risk of vision loss.
research Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-β Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by “Dystrophic Catagen” Promotion?
17-β estradiol and prednisolone may speed up hair regrowth after chemotherapy.
research Measuring steroids in hair opens up possibilities to identify congenital adrenal hyperplasia in developing countries
Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.
research Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
Neural stem cells use local feedback to maintain balance in the adult brain.
research The relationship between psychological distress and neurotrophins in patients with alopecia areata: A crosssectional study
Alopecia areata patients experience more psychological distress, linked to certain neurotrophin levels.
research Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)
Human skin can produce steroids from cholesterol.
research Possible Role of Osteopathic Manipulation Treatment in Alleviation of Finasteride-Induced Dementia through Modulation of HOMER-3 Gene Methylation
Osteopathic manipulation therapy might help treat dementia caused by finasteride.
research Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty
In STSD patients, the body compensates for low androgen levels by increasing another enzyme's activity.
research EFFECTS OF STEROID HORMONES ON DEVELOPING MOUSE SKIN IN VITRO
Cortisol and corticosterone thin mouse skin and regress hair follicles, while testosterone promotes skin and hair development.
research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors
research Glucocorticoids and mineralocorticoids in hair: facilitating accurate diagnosis of adrenal-related endocrine disorders
Hair analysis can help diagnose adrenal disorders non-invasively.
research Three-Dimensional Organoid System Transplantation Technologies in Future Treatment of Central Nervous System Diseases
Neural organoids show promise for future CNS disease treatments.
research Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.
research Neuregulin3 alters cell fate in the epidermis and mammary gland
Neuregulin3 affects cell development in the skin and mammary glands.
research Evaluation of an eucalyptus oil containing topical drug delivery system for selected steroid hormones
The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.
research Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach
Phytosterols may help manage prostate issues but are less effective than synthetic drugs.
research ENHANCEMENT OF FOLLICULAR DELIVERY OF FINASTERIDE IN NIOSOMALAND PRONIOSOMAL GEL FORM FOR TREATING ANDROGENETIC ALOPECIA
Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.
research The effects of sex-steroids and menstrual cycle/oestrous phases on knee ligament laxity in humans and rodents / Firouzeh Dehghan
Knee laxity varies with menstrual cycle phases, being highest during ovulation and menstruation, and is influenced by sex-steroids.
research The hair follicle as a neuro-immuno-endocrine organ: Implications in hair disorders and regenerative therapies
Understanding hair follicle signaling can improve hair disorder treatments.