February 2025 in “Journal of Cosmetic Dermatology” Patch testing is crucial to reduce allergic reactions in hair loss treatments.
January 1985 in “Clinical research” Topical alpha-terthienyl with UVA may safely treat psoriasis without cancer risk.
23 citations
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April 2002 in “Journal of the American Academy of Dermatology” Depigmented hair regrowth after alopecia areata can be permanent.
21 citations
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January 2023 in “Biomaterials Science” Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
November 2022 in “Journal of Investigative Dermatology” A new molecule was found to be a safe and effective skin lightener and anti-aging product.
November 2021 in “CRC Press eBooks” Hair color is determined by melanin and can be affected by genetic conditions like albinism.
22 citations
,
September 1986 in “Journal of Investigative Dermatology” Low-dose topical alpha-terthienyl may be a safer option for treating skin conditions with light therapy.
9 citations
,
July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
16 citations
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December 2016 in “Skin appendage disorders” Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
January 2025 in “Journal of Pharmacognosy and Phytochemistry” Plant-based pigments in shampoo offer vibrant colors and scalp benefits, meeting quality standards and providing a natural alternative to synthetic dyes.
2 citations
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January 2023 in “Dermatologic Therapy” CEFFE injections effectively and safely improve postinflammatory hyperpigmentation.
March 2026 in “Indian Dermatology Online Journal” Hair dye ingredient PPD can cause severe allergic reactions, including facial swelling.
April 2019 in “Journal of Investigative Dermatology” The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
December 2025 in “Scientific Reports” α-Mangostin can naturally lighten skin by reducing melanin.
January 2004 in “Side effects of drugs annual” Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
1 citations
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July 2015 in “British Journal of Dermatology” Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.
13 citations
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January 2014 in “Postępy Dermatologii i Alergologii” Patchy alopecia areata can affect only pigmented hairs, leaving gray hairs untouched.
September 2019 in “Journal of Investigative Dermatology” PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
April 2019 in “Journal of Investigative Dermatology” Eating grape powder may reduce the severity of skin allergy symptoms.
March 2026 in “Portuguese Journal of Dermatology and Venereology” Avoid hair dye after microneedling to prevent scalp pigmentation.
98 citations
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November 2002 in “Contact Dermatitis” Many people had severe allergic reactions to a common hair dye ingredient, causing them to seek medical care and miss work.
2 citations
,
August 2016 in “Lasers in Surgery and Medicine” Photodynamic therapy can remove nonpigmented hair in mice and might work for humans.
94 citations
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October 2017 in “International Journal of Dermatology” Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The natural hair dye is safe, effective, and good for scalp health.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The natural hair dye is safe, effective, and good for scalp health.
11 citations
,
July 2010 in “Dermatitis” Patch testing helps find allergens in minoxidil treatments, but doesn't ensure alternatives will be tolerated.
7 citations
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March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
6 citations
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December 2013 in “Journal of Cosmetic Dermatology” Pigmented concealing powders can improve the look of hair density for people with hair loss but need daily application and may not work well in wet conditions.
4 citations
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July 2019 in “Clinics in Dermatology” The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.