21 citations
,
January 2023 in “Biomaterials Science” Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
18 citations
,
February 2015 in “Acta Crystallographica Section D: Structural Biology” The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.
14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
4 citations
,
January 2018 in “Cosmetics” Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.
25 citations
,
September 2020 in “Molecules” Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
9 citations
,
July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
May 2026 in “Commagene Journal of Biology” Anti-aging peptides can improve skin appearance but need better delivery methods and more research.
September 2025 in “Journal of Drug Delivery Science and Technology” Vitamin D3-coated nanoparticles effectively deliver caffeine for alopecia treatment with minimal side effects.
21 citations
,
January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
September 2025 in “Cell Reports” Skin stretching can improve vaccine delivery through hair follicles and boost immune response.
10 citations
,
January 2014 in “Journal of Pharmaceutical Sciences” Balancing lipophilicity and solubility is key for effective and safe ketorolac prodrugs.
January 2012 in “Journal of Cosmetics Dermatological Sciences and Applications” Iontophoresis greatly improves skin absorption of certain substances, especially in hairy mice.
19 citations
,
October 2024 in “Molecular Pharmaceutics” Microneedles improve delivery of plant-based compounds through the skin, aiding treatments for hair loss, cancer, and wounds.
4 citations
,
May 2025 in “International Journal of Nanotechnology and Nanomedicine” Nanocarriers show promise for improving skin drug delivery in treating skin conditions.
10 citations
,
June 2023 in “Preprints.org” Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
3 citations
,
January 2022 in “Pharmaceutics” Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.
2 citations
,
October 2025 in “Chinese Medicine” Berberine delivery systems improve wound healing by enhancing bioavailability, reducing inflammation, and promoting tissue regeneration.
November 2025 in “Pharmacological Research” Plant-derived nanoparticles from Polygoni Multiflori Radix promote hair growth better than Minoxidil by affecting androgen pathways.
August 2025 in “MedComm – Biomaterials and Applications” Liposomal delivery systems improve drug absorption through the skin, offering potential for better treatments.
January 2025 in “AAPS PharmSciTech” Transethosomes improve drug delivery through the skin and show promise for treating various conditions.
September 2023 in “Pharmaceuticals” Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.
9 citations
,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
91 citations
,
August 2024 in “Acta Pharmaceutica Sinica B” Microneedles can improve skin disease treatment by delivering drugs directly through the skin.
48 citations
,
January 2024 in “Frontiers in Pharmacology” Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
48 citations
,
July 2023 in “Biomedicines” Hydrogel-forming microneedles are promising for safe, efficient, and controlled drug delivery through the skin.
42 citations
,
June 2021 in “Pharmaceutics” 3D printing can make microneedles for drug delivery faster and cheaper.
21 citations
,
June 2024 in “Pharmaceuticals” Swellable microneedles could improve drug delivery and diagnostics but need more research on materials and technology integration.
14 citations
,
December 2024 in “Pharmaceutics” Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.
4 citations
,
January 2022 in “Yonsei Medical Journal” Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
2 citations
,
August 2023 in “Pharmaceutics” New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.