116 citations
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April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
182 citations
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November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
4 citations
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March 2015 in “Australasian Journal of Dermatology” Hair loss is linked to insulin resistance in women, regardless of hormone levels.
IP-PA1 helps grow hair in mice and affects human cell growth-related genes differently than traditional hair growth treatments.
16 citations
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January 2023 in “Gynecological Endocrinology” Liver damage in PCOS is linked to iron overload and cell death due to the miR-761-hepcidin/GPX4 pathway.
December 2023 in “Migration letters” Herbal treatments can help manage PCOS symptoms.
May 2019 in “Journal of Clinical Dermatology” Metformin helps hair growth by affecting cell signals related to hair follicle development.
March 2019 in “Evidence Based Women Health Journal (Online)” Vitamin D supplements increased ovulation rates in women with PCOS who were vitamin D deficient.
22 citations
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October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
October 2016 in “Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei” Using a combined treatment of minoxidil and metformin can improve hair loss in women by normalizing hormone and metabolism levels.
May 1981 in “Inpharma (Balgowlah)” Medroxyprogesterone acetate improved sleep apnea symptoms in some obese patients.
2 citations
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October 2024 in “Endocrine Connections” Lower adiponectin levels are linked to higher insulin resistance in women with PCOS.
57 citations
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May 1986 in “Clinics in endocrinology and metabolism” Androstanediol glucuronide is a reliable marker for hirsutism in women.
93 citations
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May 2010 in “European Journal of Cancer” BI 2536 had limited effectiveness against several advanced cancers and caused significant side effects.
24 citations
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May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
14 citations
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June 2024 in “Food Chemistry X” Pomegranate leaf shows promise for health benefits, but more human trials are needed.
333 citations
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March 2000 in “Proceedings of the National Academy of Sciences” Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.
October 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Rodent models of PCOS show some similar and some different lipid changes compared to humans.
24 citations
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January 2023 in “Frontiers in Medicine” Moist Exposed Burn Ointment speeds up healing of diabetic wounds.
8 citations
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June 2023 in “European Journal of Endocrinology” The inhibitor affects androgen metabolism but not ovarian function.
April 2010 in “Nature Reviews Urology”
March 2025 in “Journal of Endocrinology and Metabolism” Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
19 citations
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November 2012 in “Journal of Dermatological Treatment” Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.
49 citations
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March 2009 in “Archives of Gynecology and Obstetrics” Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.
January 2011 in “Yearbook of Endocrinology”
May 2025 in “Experimental Dermatology” Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.
September 2024 in “Advanced Biomedical Research” Auriculotherapy and Aslagh capsules are as effective as metformin for treating PCOS symptoms, with auriculotherapy slightly better for reducing hair growth.
November 2025 in “Cureus” PCOS-related acne can be managed by targeting hormones and insulin resistance.
May 2020 in “International Journal of Clinical Obstetrics and Gynaecology” The combined therapy improved symptoms in PCOS patients.
3 citations
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September 2025 in “Frontiers in Cardiovascular Medicine” Women with PCOS have a higher risk of heart disease.