318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
163 citations
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October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
10 citations
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May 2025 in “Nutrition & Metabolism” Metabolic syndrome is linked to skin diseases, requiring integrated treatment and monitoring.
2 citations
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November 2025 in “Cells” Adipose-derived stem cell secretome is a promising and effective treatment for skin repair.
2 citations
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January 2025 in “International Journal of Molecular Sciences” Chitosan-encapsulated Cordyceps militaris reduces lung cell damage from pollution.
1 citations
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November 2025 in “Molecules” Ellagic acid can help treat skin issues, but its effectiveness is limited by poor absorption, so new delivery methods are being explored.
February 2026 in “International Journal of Molecular Sciences” Targeting mitochondria can improve skin healing and rejuvenation.
January 2026 in “Aging and Disease” Targeting mitochondria can improve skin health and slow aging.
June 2025 in “IntechOpen eBooks” Exosomes may improve skin and hair treatments but need more research for safe use.
June 2025 in “Dermatopathology” Dupilumab and COVID-19 can worsen or trigger psoriasis.
March 2026 in “International Journal of Molecular Sciences” Grateloupia angusta extract helps heal wounds faster and improve skin repair.
August 2025 in “Drug Design Development and Therapy” Current treatments for androgenetic alopecia are complex and promising, but more research is needed.
51 citations
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March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
45 citations
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January 2021 in “Stem Cell Research & Therapy” The combination of stem cell medium and hydrogel effectively reduces and improves hypertrophic scars.
42 citations
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September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
18 citations
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February 2024 in “ACS Polymers Au” Silk fibroin shows promise for wound care but faces challenges in becoming widely available.
3 citations
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February 2025 in “Frontiers in Cell and Developmental Biology” Wharton's Jelly stem cell medium may help treat skin issues in Systemic Sclerosis.
March 2022 in “IntechOpen eBooks” Botulinum Neurotoxin-A can treat acne, oily skin, rosacea, hair loss, prevent scars, relieve nerve pain, reduce excessive sweating, and manage psoriasis, but more trials are needed to confirm its effectiveness.
1425 citations
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September 2020 in “Open Biology” Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
328 citations
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November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
154 citations
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November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
142 citations
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March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
56 citations
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November 2022 in “Biomolecules” Targeting macrophages may improve wound healing.
56 citations
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October 2007 in “Journal of Biological Chemistry” Cathepsin L is essential for heart health and its absence causes heart problems and hair loss.
50 citations
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March 2021 in “Annals of Translational Medicine” More research is needed to understand and treat morphea effectively.
14 citations
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July 2022 in “Applied Sciences” Extracellular vesicles can help repair and regenerate tissues with less risk of rejection.
12 citations
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November 2024 in “Burns & Trauma” Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
9 citations
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August 2025 in “Current Issues in Molecular Biology” Extracellular vesicles can help regenerate bones but need more research for safe clinical use.
9 citations
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May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
6 citations
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June 2024 in “Medical Review” Biliary fibrosis is crucial in liver diseases and understanding it can help prevent and treat these conditions.