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420-450 / 1000+ resultsresearch Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation
Peptide-based PROTACs show promise in targeting hard-to-treat proteins, especially for cancer therapy.
research Droplets-Based Microfluidics as a Platform to Design Food-Grade Delivery Systems Based on the Entrapped Compound Type
Droplet-based microfluidics improves delivery of bioactive compounds in food using precise encapsulation and release.
research Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs
A new method allows detailed tracking of cell regeneration in crustacean legs.
research Engineering Cell‐Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research A microfluidic application for mass production of drug-loaded polymeric microspheres for a long-acting injectable with IVL-DrugFluidic®, a novel microfluidic microsphere manufacturing platform technology
IVL-DrugFluidic® can mass-produce high-quality, long-acting injectable drug microspheres, improving patient compliance and reducing side effects.
research In Situ Self-Assembling Liver Spheroids with Synthetic Nanoscaffolds for Preclinical Drug Screening Applications
PCL nanoscaffold-based liver spheroids are effective for drug screening and studying liver toxicity.
research The sternum reconstruction: Present and future perspectives
New techniques and materials improve sternum reconstruction and patient quality of life.
research Dermacen Analytica: A Novel Methodology Integrating Multi-Modal Large Language Models with Machine Learning in tele-dermatology
The new AI system improves remote skin condition diagnosis and access to care.
research New frontiers in CRISPR/Cas9 delivery systems delivery for gene editing
Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
research Optimized polycystic ovarian disease prognosis and classification using AI based computational approaches on multi-modality data
AI can improve early diagnosis and classification of PCOS, aiding in prevention of related health issues.
research De novo designed bifunctional proteins for targeted protein degradation
Newly designed proteins can effectively degrade specific proteins in cells, offering a promising alternative for targeted protein degradation.
research Harnessing Regenerative Science in Aesthetic Surgery: The Biologically Driven Future
Regenerative medicine could revolutionize aesthetic surgery, but needs careful validation and ethical use.
research Engineered building bloks to print endogenous tissue and complex organs in vitro
New bio-ink can print complex tissues and organs.
research Chaotrope-Guided Protein Microneedles with High Drug-Loading Capacity, Ultrafast Dissolution, and High Mechanical Strength
research Life Sciences Discovery and Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
research The composition of cell‐based therapies obtained from point‐of‐care devices/systems which mechanically dissociate lipoaspirate: a scoping review of the literature
It's unclear if cell-based therapies from lipoaspirate devices improve clinical outcomes due to inconsistent data.
research 575 INTASYL self-delivering RNAi: A flexible platform to treat dermatological malignancies
INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
research Modeling share dynamics by extracting competition structure
The model can predict website market shares by identifying competition among them.
research 779 Multicellular skin organoids as a unique modeling platform for skin physiology, injury, and disease
The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
research Can Artificial Intelligence Support Patient Education in Scabies? A Comparative Analysis of Large Language Model Responses
AI chatbots can help with scabies education but shouldn't replace doctors.
research Global Research Trends in Extracellular Vesicle–Based Therapy for Regenerative Medicine: A Bibliometric Analysis (2014–2024)
EV-based therapies are advancing but need to overcome challenges for full potential.
research Letters to the Editors: Re: Role of automated devices in hair restoration
Automated devices are beneficial for hair restoration.
research Nanogenerators in Biomedical Frontiers: Revolutionizing Self-Powered Healthcare Systems
Self-powered nanogenerators could revolutionize healthcare by enabling devices that operate without external power.
research Triboelectric Nanogenerators for Therapeutic Electrical Stimulation
Triboelectric nanogenerators can use body movement to power therapeutic treatments, potentially transforming personalized healthcare.
research Strategy for Generating Blinded Evidence for Single-Arm Trials with External Controls Using Expert Review of Home Video
A new method uses expert reviews of home videos to objectively assess children's developmental milestones in single-arm trials.
research A New Multi-Graft Implanter System
The new system makes hair transplants faster and more precise.
research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.