research PROTACs in 2025: from the laboratory concept to clinical breakthrough
PROTACs have become a breakthrough in medicine by effectively targeting and degrading specific proteins to treat diseases.
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research Trends in the global organoid technology and industry: from organogenesis in a dish to the commercialization of organoids
Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
research Stimuli-responsive hydrogels for radiation-induced skin injury: from passive barriers to autonomous drug delivery systems
Advanced hydrogels can autonomously deliver drugs to treat radiation skin injuries, but challenges remain for clinical use.
research QuantAnts machines discover biomarkers for RAS signaling activation and design sgRNAs for CRISPR to target complex CD9, CD34, and CD74.
The QuantAnts machines can find cancer markers and create CRISPR targets for them.
research LIGA R and D and prototyping[Lithography, Electroforming, and Assembly]
research Minimizing Factual Inconsistency and Hallucination in Large Language Models
A new method improves the accuracy and reliability of language models by up to 42%.
research 3D Bioprinting Skin Equivalents: A Methodological Perspective on Human Keratinocyte and Fibroblast Models for Wound Repair and Regeneration
3D bioprinting shows promise for creating skin substitutes, but standardized methods are needed for clinical use.
research Nature-skin-based multi-responsive controlled-release electroactive scaffolds for integrated melanoma postoperative relapse prevention and wound therapy
The scaffold effectively prevents melanoma relapse and aids wound healing.
research Innovative approaches to baldness detection and management with artificial intelligence and machine learning
research Modern Polycystic Ovary Syndrome (PCOS) Management: Intelligent Drug Delivery and Metabolic Reprogramming for Ovarian Restoration and Fertility Optimization
New treatments for PCOS using smart drug delivery, metabolic changes, and AI show promise but need more research.
research Research Advances in Therapeutic Strategies and Drug Delivery Systems for Pathological Scars
New drug delivery systems show promise in effectively treating pathological scars.
research Three-dimensional models: from cell culture to Patient-Derived Organoid and its application to future liposarcoma research
3D models and organoids improve liposarcoma research and therapy development.
research Self-Organizing 3D Dermal Papilla Cell Spheroids Yield Therapeutic Extracellular Vesicles that Target Hypertrophic Scar Regression via the miR-26a-5p/CCNE2 Axis
3D cell spheroids can help reduce scars by delivering therapeutic vesicles.
research High-Throughput 3D Spheroid Production with Photocurable Polyurethane Microwell Arrays via LCD 3D Printing
The method effectively creates uniform, viable cell spheroids for 3D cell culture.
research Σχεδιασμός και υλοποίηση συστήματος επεξεργασίας εικόνας καθώς και μαθηματικών αλγορίθμων βελτιστοποίησης της μεταμόσχευσης ανθρωπίνων τριχοθυλακίων με την τεχνική FUE
The document concludes that the FOLLYSIS© system improves hair transplant processes and patient monitoring with high accuracy and less skin trauma.
research Hydrogel Lego based on rehydrated laminate assembly for standardized production and customized integration of multifunctional hydrogel sensors
New hydrogel sensors can be quickly made and customized for wearable devices.
research Stiffness-Controlled Thermoresponsive Hydrogels for Cell Harvesting with Sustained Mechanical Memory
The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.
research Developing Humanized Animal Models with Transplantable Human iPSC-Derived Cells
Humanized animal models using human stem cells can improve disease research and drug testing.
research Drug Delivery Applications of Three-Dimensional Printed (3DP) Mesoporous Scaffolds
3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.
research Self-adaptive nanozymes with enhanced multi-enzyme activities for sequential multimodal therapy of drug-resistant bacteria-infected wounds
The new treatment effectively heals drug-resistant bacteria-infected wounds.
research Innovations in Skin Regeneration: The Intersection of 3D Bioprinting and Single-Cell RNA Sequencing
Combining 3D bioprinting and single-cell RNA sequencing improves skin regeneration.
research Spanlastics: An Innovative Nanovesicular Platform for Advanced Drug Delivery
Spanlastics improve drug delivery by enhancing bioavailability and targeting, reducing side effects.
research Degradation of human hair keratin scaffold implanted for repairing injured skeletal muscles.
Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.
research The Bioengineering of Microspheric Skin Organoids and Their Application in Drug Screening
Microspheric skin organoids can be used for drug testing, identifying Minoxidil as a Wnt pathway activator.
research 565 hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction
Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
research Droplet-Based Microfluidics as a Platform to Design Food-Grade Delivery Systems Based on the Entrapped Compound Type
Microfluidics can create precise, efficient delivery systems for food and cosmetics, but scaling up is challenging.
research Application of Scaffold-Based Drug Delivery in Oral Cancer Treatment: A Novel Approach
Scaffold-based drug delivery systems improve oral cancer treatment by targeting drugs directly to cancer cells, reducing side effects.
research Contract cheating websites in Spain (2019–2024): web traffic trends during COVID-19 and the rise of generative AI
Contract cheating website traffic in Spain surged during COVID-19 but declined with the rise of AI tools.
research Scalable fabrication, compartmentalization and applications of living microtissues
Continuous microfluidic processes can help scale up microtissue production for industrial and clinical use.
research A 3D microtumour system that faithfully represents ovarian cancer minimal residual disease
The study developed a 3D model that closely imitates remaining ovarian cancer after treatment and identified a potential drug targeting resistant cancer cells.