October 2025 in “International Journal of Cell and Biomedical Science” hUC-MSC secretome can help regrow hair in cases of hair loss.
August 2024 in “International Journal of Basic & Clinical Pharmacology” Secretome-based therapies could improve hair growth better than current treatments.
January 2023 in “Open veterinary journal” Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.
773 citations
,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
54 citations
,
August 2019 in “Bioscience trends” Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.
18 citations
,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
May 2024 in “International journal of nanomedicine” Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.
April 2024 in “Journal of cancer research and clinical oncology” Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.
March 2024 in “Drug development & registration” Mesenchymal stem cell secretome shows promise for skin treatments but needs more human trials.
46 citations
,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
21 citations
,
March 2025 in “Journal of Extracellular Vesicles” Hydrogels can enhance stem cell activity, but more research is needed to optimize their use.
1 citations
,
November 2025 in “Stem Cell Research & Therapy” Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
11 citations
,
July 2015 in “Journal of Anatomy” SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
6 citations
,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
May 2026 in “International Journal of Molecular Sciences” Plucked hair follicles can be used for regenerative therapies and personalized medicine.
May 2023 in “Cytotherapy” Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.
106 citations
,
August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
76 citations
,
February 2021 in “International Journal of Molecular Sciences” Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
51 citations
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April 2020 in “Cells” Special cell particles from macrophages can help hair grow.
19 citations
,
January 2023 in “Frontiers in Bioengineering and Biotechnology” MSC-sEVs may effectively treat chronic non-healing wounds.
16 citations
,
March 2025 in “International Journal of Molecular Sciences” Extracellular vesicles show promise in skin treatments but need more research and standardization.
15 citations
,
January 2009 in “International Journal of Andrology” Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.
10 citations
,
September 2021 in “International Journal of Nanomedicine” Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
9 citations
,
May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
8 citations
,
June 2022 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles show promise for skin improvement and anti-aging in facial care but face challenges like low production and lack of research.
7 citations
,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
6 citations
,
July 2022 in “World journal of stem cells” Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.
4 citations
,
May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles may help prevent and repair spine disc degeneration.
3 citations
,
September 2025 in “Cosmetics” Extracellular vesicles could revolutionize skincare by improving skin repair and anti-aging, but face regulatory and cost challenges.
2 citations
,
September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.