research Grand challenges in dermatologic drug discovery: four priorities to transform skin disease treatment
Transforming skin disease treatment requires new strategies, better drug models, and patient-focused research.
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research Development of novel wound dressing based on elastin-like recombinamers for skin regeneration
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research Skin connective tissue and ageing
Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.
research Study on the mechanism of cadmium chloride pollution accelerating skin tissue metabolism disorder, aging and inhibiting hair regeneration
Cadmium chloride pollution can cause skin disorders, speed up aging, and prevent hair growth.
research Applications of Mesenchymal Stem Cells in Anti-Aging and Skin Regeneration
Mesenchymal stem cells can help delay skin aging and improve wound healing.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research MiR-23b and miR-133 cotarget TGFβ2/NOTCH1 in dermal fibroblasts and affect hair follicle development in sheep
Two microRNAs affect hair follicle development in sheep by targeting specific genes.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research From skin microrelief to wrinkles. An area ripe for investigation
Wrinkles form due to structural skin changes and vary in type and treatment response.
research Vascular endothelial cells as signaling niches for epithelial stem cells in the skin
Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
research Exosomes in Skin of Color: Dermatological Insights, Therapeutic Potential, and Clinical Realities in India
Exosomes show promise for skin treatments but need more research and regulation in India.
research Clinical and biological impact of the exposome on the skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
research Hair follicle dermal stem cells and skin‐derived precursor cells: Exciting tools for endogenous and exogenous therapies
Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
research Stem cells and the skin
Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
research Mechanotransductive Differentiation of Hair Follicle Stem Cells Derived from Aged Eyelid Skin into Corneal Endothelial-Like Cells
Hair follicle stem cells from aged eyelid skin can become corneal endothelial-like cells for potential eye treatments.
research Morphological changes in the skin in a rat model of stress-induced alopecia and their correction with nutrients
A nutrient-rich diet improved skin and hair health in stressed rats.
research Effect of carbon dioxide laser (10600nm) on hydroxyproline in mouse skin
CO2 laser treatment may be more effective for skin rejuvenation.
research 898 Homeostatic activation of epidermal HSD11b1 affects skin innervation and non-histaminergic itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging
Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
research Aromatic plants as cosmeceuticals: benefits and applications for skin health
Aromatic plants can naturally help prevent skin aging and improve skin health.
research Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney
Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
research Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes
Certain genes are linked to skin aging, like wrinkles and pigmentation changes.
research Mushrooms Natural Products Cosmetic Weapons as Anti-Hair Loss, Anti-Ageing Skin and Future Prospect
Mushroom extracts can help with anti-aging, skin care, and hair loss in cosmetics.
research Exosomes in Skin Rejuvenation: Systematic Review of Anti-Aging Effects and Clinical Applications
Exosomes can improve skin elasticity, reduce wrinkles, and enhance hydration, but more research is needed.
research Gender Differences in Production and Circulating Levels of Sex Hormones and Their Impact on Aging Skin
Men and women experience skin aging differently due to changes in sex hormone levels with age.
research Skin physiology in microgravity: a 3-month stay aboard ISS induces dermal atrophy and affects cutaneous muscle and hair follicles cycling in mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.